Design and optimization of genetically encoded biosensors for high-throughput screening of chemicals

HG Lim, S Jang, S Jang, SW Seo, GY Jung - Current opinion in …, 2018 - Elsevier
Highlights•Genetically encoded biosensors are used in evolutionary metabolic
engineering.•These biosensors are constructed from natural or artificial genetic …

Biocatalytic gateway to convert glycerol into 3-hydroxypropionic acid in waste-based biorefineries: Fundamentals, limitations, and potential research strategies

HM Zabed, S Akter, PF Rupani, J Akor, Y Zhang… - Biotechnology …, 2023 - Elsevier
Microbial conversion of bioenergy-derived waste glycerol into value-added chemicals has
emerged as an important bioprocessing technology due to its eco-friendliness, feasible …

Hyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis

XR Jiang, X Yan, LP Yu, XY Liu, GQ Chen - Nature communications, 2021 - nature.com
Hydroxypropionic acid (3HP), an important three carbon (C3) chemical, is designated as
one of the top platform chemicals with an urgent need for improved industrial production …

Recent advances, challenges and metabolic engineering strategies in the biosynthesis of 3‐hydroxypropionic acid

B Liang, G Sun, X Zhang, Q Nie… - Biotechnology and …, 2022 - Wiley Online Library
As an attractive and valuable platform chemical, 3‐hydroxypropionic acid (3‐HP) can be
used to produce a variety of industrially important commodity chemicals and biodegradable …

Circuit-guided population acclimation of a synthetic microbial consortium for improved biochemical production

CW Kang, HG Lim, J Won, S Cha, G Shin… - Nature …, 2022 - nature.com
Microbial consortia have been considered potential platforms for bioprocessing applications.
However, the complexity in process control owing to the use of multiple strains necessitates …

In vivo biosensors: mechanisms, development, and applications

S Shi, EL Ang, H Zhao - Journal of Industrial Microbiology and …, 2018 - academic.oup.com
In vivo biosensors can recognize and respond to specific cellular stimuli. In recent years,
biosensors have been increasingly used in metabolic engineering and synthetic biology …

Directed evolution of the 3-hydroxypropionic acid production pathway by engineering aldehyde dehydrogenase using a synthetic selection device

JY Seok, J Yang, SJ Choi, HG Lim, UJ Choi, KJ Kim… - Metabolic …, 2018 - Elsevier
Hydroxypropionic acid (3-HP) is an important platform chemical, and biological production of
3-HP from glycerol as a carbon source using glycerol dehydratase (GDHt) and aldehyde …

Transcription factor engineering for high-throughput strain evolution and organic acid bioproduction: a review

JW Li, XY Zhang, H Wu, YP Bai - Frontiers in Bioengineering and …, 2020 - frontiersin.org
Metabolic regulation of gene expression for the microbial production of fine chemicals, such
as organic acids, is an important research topic in post-genomic metabolic engineering. In …

Production of 3-hydroxypropionic acid in engineered Methylobacterium extorquens AM1 and its reassimilation through a reductive route

YM Yang, WJ Chen, J Yang, YM Zhou, B Hu… - Microbial cell …, 2017 - Springer
Abstract Background 3-Hydroxypropionic acid (3-HP) is an important platform chemical,
serving as a precursor for a wide range of industrial applications such as the production of …

Characterisation of a 3-hydroxypropionic acid-inducible system from Pseudomonas putida for orthogonal gene expression control in Escherichia coli and Cupriavidus …

EKR Hanko, NP Minton, N Malys - Scientific reports, 2017 - nature.com
hydroxypropionic acid (3-HP) is an important platform chemical used as a precursor for
production of added-value compounds such as acrylic acid. Metabolically engineered yeast …