Neurovascular coupling: motive unknown

PJ Drew - Trends in neurosciences, 2022 - cell.com
In the brain, increases in neural activity drive changes in local blood flow via neurovascular
coupling. The common explanation for increased blood flow (known as functional …

Lights, fiber, action! A primer on in vivo fiber photometry

EH Simpson, T Akam, T Patriarchi, M Blanco-Pozo… - Neuron, 2024 - cell.com
Fiber photometry is a key technique for characterizing brain-behavior relationships in vivo.
Initially, it was primarily used to report calcium dynamics as a proxy for neural activity via …

Sensitive multicolor indicators for monitoring norepinephrine in vivo

Z Kagiampaki, V Rohner, C Kiss, S Curreli, A Dieter… - Nature …, 2023 - nature.com
Genetically encoded indicators engineered from G-protein-coupled receptors are important
tools that enable high-resolution in vivo neuromodulator imaging. Here, we introduce a …

Toward Plasmonic Neural Probes: SERS Detection of Neurotransmitters through Gold‐Nanoislands‐Decorated Tapered Optical Fibers with Sub‐10 nm Gaps

D Zheng, F Pisano, L Collard, A Balena… - Advanced …, 2023 - Wiley Online Library
Integration of plasmonic nanostructures with fiber‐optics‐based neural probes enables label‐
free detection of molecular fingerprints via surface‐enhanced Raman spectroscopy (SERS) …

Sub-100 ms level ultrafast detection and near-infrared ratiometric fluorescence imaging of norepinephrine in live neurons and brains

Y Han, L Mao, QW Zhang, Y Tian - Journal of the American …, 2023 - ACS Publications
Norepinephrine (NE) is a key neurotransmitter in the central and sympathetic nervous
systems, whose content fluctuates dynamically and rapidly in various brain regions during …

Unraveling the dynamics of dopamine release and its actions on target cells

T Sippy, NX Tritsch - Trends in neurosciences, 2023 - cell.com
The neuromodulator dopamine (DA) is essential for regulating learning, motivation, and
movement. Despite its importance, however, the mechanisms by which DA influences the …

Recent advances in the development and characterization of electrochemical and electrical biosensors for small molecule neurotransmitters

J He, E Spanolios, CE Froehlich, CL Wouters… - ACS …, 2023 - ACS Publications
Neurotransmitters act as chemical messengers, determining human physiological and
psychological function, and abnormal levels of neurotransmitters are related to conditions …

Aptamer conformational dynamics modulate neurotransmitter sensing in nanopores

A Stuber, A Douaki, J Hengsteler, D Buckingham… - Acs Nano, 2023 - ACS Publications
Aptamers that undergo conformational changes upon small-molecule recognition have been
shown to gate the ionic flux through nanopores by rearranging the charge density within the …

Advanced near‐infrared light approaches for neuroimaging and neuromodulation

H Yin, W Jiang, Y Liu, D Zhang, F Wu, Y Zhang, C Li… - …, 2023 - Wiley Online Library
Almost all physiological processes of animals are controlled by the brain, including
language, cognitive, memory, learning, emotion and so forth. Minor brain dysfunction usually …

Inflammation-free electrochemical in vivo sensing of dopamine with atomic-level engineered antioxidative single-atom catalyst

X Gao, H Wei, W Ma, W Wu, W Ji, J Mao, P Yu… - Nature …, 2024 - nature.com
Electrochemical methods with tissue-implantable microelectrodes provide an excellent
platform for real-time monitoring the neurochemical dynamics in vivo due to their superior …