Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child

PM Catalano, K Shankar - Bmj, 2017 - bmj.com
Obesity is the most common medical condition in women of reproductive age. Obesity during
pregnancy has short term and long term adverse consequences for both mother and child …

Influence of maternal obesity on the long-term health of offspring

KM Godfrey, RM Reynolds, SL Prescott… - The lancet Diabetes & …, 2017 - thelancet.com
In addition to immediate implications for pregnancy complications, increasing evidence
implicates maternal obesity as a major determinant of offspring health during childhood and …

Early developmental conditioning of later health and disease: physiology or pathophysiology?

MA Hanson, PD Gluckman - Physiological reviews, 2014 - journals.physiology.org
Extensive experimental animal studies and epidemiological observations have shown that
environmental influences during early development affect the risk of later pathophysiological …

Maternal obesity and occurrence of fetal macrosomia: a systematic review and meta‐analysis

L Gaudet, ZM Ferraro, SW Wen… - BioMed research …, 2014 - Wiley Online Library
Objective. To determine a precise estimate for the contribution of maternal obesity to
macrosomia. Data Sources. The search strategy included database searches in 2011 of …

Metformin versus placebo in obese pregnant women without diabetes mellitus

A Syngelaki, KH Nicolaides, J Balani… - … England Journal of …, 2016 - Mass Medical Soc
Background Obesity is associated with an increased risk of adverse pregnancy outcomes.
Lifestyle-intervention studies have not shown improved outcomes. Metformin improves …

[HTML][HTML] Maternal obesity during pregnancy and cardiovascular development and disease in the offspring

R Gaillard - European journal of epidemiology, 2015 - Springer
Maternal obesity during pregnancy is an important public health problem in Western
countries. Currently, obesity prevalence rates in pregnant women are estimated to be as …

Gestational weight gain: update on outcomes and interventions

ML Champion, LM Harper - Current diabetes reports, 2020 - Springer
Abstract Purpose of Review Gestational weight gain is a modifiable risk factor for adverse
perinatal outcomes. After the Institute of Medicine (IOM) released updated recommendations …

[HTML][HTML] Associations of maternal BMI and gestational weight gain with neonatal adiposity in the Healthy Start study

AP Starling, JT Brinton, DH Glueck, AL Shapiro… - The American journal of …, 2015 - Elsevier
Background: Maternal obesity and weight gain during pregnancy are risk factors for child
obesity. Associations may be attributable to causal effects of the intrauterine environment or …

Current review of genetics of human obesity: from molecular mechanisms to an evolutionary perspective

D Albuquerque, E Stice, R Rodríguez-López… - Molecular genetics and …, 2015 - Springer
It is well-known that obesity is a complex multifactorial and heterogeneous condition with an
important genetic component. Recently, major advances in obesity research emerged …

Association of maternal weight gain in pregnancy with offspring obesity and metabolic and vascular traits in childhood

A Fraser, K Tilling, C Macdonald-Wallis, N Sattar… - Circulation, 2010 - Am Heart Assoc
Background—We sought to examine the association of gestational weight gain (GWG) and
prepregnancy weight with offspring adiposity and cardiovascular risk factors. Methods and …