The utilizations of microfluidic chips for single RBC (red blood cell) studies have attracted
great interests in recent years to filter, trap, analyze, and release single erythrocytes for …

The regulation of polymorphonuclear leukocyte (PMN) function by mechanical forces
encountered during their migration across restrictive endothelial cell junctions is not well …

The clearance of senescent and altered red blood cells (RBCs) in the red pulp of the human
spleen involves sequential processes of prefiltration, filtration, and postfiltration. While prior …

The spleen, the largest secondary lymphoid organ in humans, not only fulfils a broad range
of immune functions, but also plays an important role in red blood cell's (RBC) life cycle …

Understanding the homing dynamics of individual mesenchymal stem cells (MSCs) in
physiologically relevant microenvironments is crucial for improving the efficacy of MSC …

The splenic interendothelial slits fulfill the essential function of continuously filtering red
blood cells (RBCs) from the bloodstream to eliminate abnormal and aged cells. To date, the …

We overview recent advances in the theoretical modeling, in particular via numerical
simulation, of various vital human erythrocyte phenomena. The review is novel in how it …

Numerical simulation of blood flow is a challenging topic due to the multiphase nature of this
biological fluid. The choice of a specific method among the ones available in literature is …

Erythrophagocytosis occurring in the spleen is a critical process for removing senescent and
diseased red blood cells (RBCs) from the microcirculation. Although some progress has …

Normal red blood cells (RBCs) have remarkable properties of deformability, which enable
them to squeeze through tiny splenic inter-endothelial slits (IESs) without any damage …