Migraine is an extremely disabling, common neurological disorder characterized by a
complex neurobiology, involving a series of central and peripheral nervous system areas …

The underlying causes of migraine headache remained enigmatic for most of the 20th
century. In 1979, The Lancet published a novel hypothesis proposing an integral role for the …

Plaguing humans for more than two millennia, manifest on every continent studied, and with
more than one billion patients having an attack in any year, migraine stands as the sixth …

Objective The goal of this narrative review is to provide an overview of migraine
pathophysiology, with an emphasis on the role of calcitonin gene‐related peptide (CGRP) …

Sensitization of trigeminal ganglion neurons contributes to primary headache disorders such
as migraine, but the specific neuronal and non-neuronal trigeminal subtypes that are …

Understanding the mechanisms of migraine remains challenging as migraine is not a static
disorder, and even in its episodic form migraine remains an “evolutive” chronic condition …

Migraine is a prevalent disorder, affecting 15.1% of the world's population. In most cases, the
migraine attacks are sporadic; however, some individuals experience a gradual increase in …

Migraine is a common, chronic, disorder that is typically characterized by recurrent disabling
attacks of headache and accompanying symptoms, including aura. The aetiology is …

Migraine is a common, multifactorial, disabling, recurrent, hereditary neurovascular
headache disorder. It usually strikes sufferers a few times per year in childhood and then …

Migraine is a primary headache disorder characterized by a unilateral, throbbing, pulsing
headache, which lasts for hours to days, and the pain can interfere with daily activities. It …