Simple Summary T-cell lymphomas are a rare, heterogeneous family of lymphomas derived
from post-thymic T lymphocytes. For patients with relapsed or refractory disease, outcomes …

Simple Summary The genetic landscape of cutaneous T-cell lymphomas analyzed by
sequencing high throughput techniques shows a heterogeneous somatic mutational profile …

Background Malignant clones of primary cutaneous T-cell lymphomas (CTCL) can show a
CD4+, CD8+ or T-cell receptor (TCR)-γδ+ phenotype, but their individual impact on tumour …

The classification of primary cutaneous lymphomas and lymphoproliferative disorders (LPD)
is continuously evolving by integrating novel clinical, pathological and molecular data …

Simple Summary Cutaneous T-cell lymphomas (CTCLs) are a rare kind of skin cancer that
currently has no curative treatment except allogeneic stem cell transplantation. The aim of …

Nodal peripheral T-cell lymphomas (PTCL) are uncommon and heterogeneous tumors
characterized by a dismal prognosis. Targeted therapy has been proposed. However …

Cutaneous 5T cell lymphoma (CTCL), characterized by malignant T cells infiltrating the skin
with potential for dissemination, remains a challenging disease to diagnose and treat due to …

Cutaneous T-cell lymphomas (CTCL) are a heterogeneous group of non-Hodgkin's
lymphomas (NHL) characterised by the clonal proliferation of malignant, skin homing T-cells …

While normal B-and T-lymphocytes require antigenic ligands to become activated via their B-
and T-cell receptors (BCR and TCR, respectively), B-and T-cell lymphomas show the broad …

Recurrent gene rearrangements result in gene fusions that encode chimeric proteins, driving
the pathogenesis of many hematologic neoplasms. The fifth edition World Health …