Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary
cystic kidney disease, with patients often having a positive family history that is characterized …

Fibroblast growth factor 23 (FGF23) and parathyroid hormone blood levels rise following
progressive loss of renal function. Here we measured parameters of phosphate metabolism …

Results ADPKD patients had 50% higher FGF23 levels than did XLH patients; TmP/GFR
was near normal in most ADPKD patients and very low in XLH patients. Serum Klotho levels …

Sirolimus has been approved for clinical use in non proliferative and proliferative disorders.
It inhibits the mammalian target of rapamycin (mTOR) signaling pathway which is also …

The failure of the polycystins (PCs) to function in primary cilia is thought to be responsible for
autosomal dominant polycystic kidney disease (ADPKD). Primary cilia integrate multiple …

Objective Autosomal dominant polycystic kidney disease (ADPKD) is mainly caused by the
pathogenic mutation of PKD1 or PKD2 gene and usually affects bilateral kidneys …

TORREGROSA, José V. et al. Tratamiento eficaz de la arteriolopatía urémica calcificante
con bifosfonatos. Nefrología (Madr.)[online]. 2012, vol. 32, n. 3, pp. 329-334. ISSN 0211 …

Key Clinical Message We present the case of a 41‐year‐old man patient diagnosed with
solitary left kidney with few cysts. He has a family history of unilateral renal agenesis (URA) …

Background Autosomal dominant polycystic kidney disease (ADPKD) is the most common
hereditary renal disorder. In most cases, ADPKD similarly affects bilateral kidneys. Case …

Background: The major cause of hereditary renal failure is autosomal dominant polycystic
kidney disease (ADPKD). Many factors affect renal progression in these patients. Among …