Inflammatory bowel disease (IBD) represents chronic recurrent intestinal inflammation
resulting from various factors. Crohn's disease (CD) and ulcerative colitis (UC) have been …

Abstract Background Sophora flavescens Aiton (SF), also known as Kushen (Chinese: 苦参),
has been an important species in Chinese medicine since the Qin and Han dynasties. It is …

Quinolizidine alkaloids (QAs) are nitrogen-containing compounds produced naturally as
specialized metabolites distributed in plants and animals (eg, frogs, sponges). The present …

Phytochemical investigation of Sophora secundiflora alkaloid fraction led to isolation of one
new quinolizidine alkaloid (1) 13-methoxyanagyrine together with six known ones (2–7) …

Herein we describe a method to produce 2-haloalkoxy-3-substituted quinolines via the
cyclization of 2-alkynylanilines with TMSCF3 and THF. This synthetic method uses …

Main observation and conclusion A phytochemical investigation on the seeds of Sophora
alopecuroides led to obtaining fourteen structurally diverse matrine‐based alkaloids (1 …

Ethnopharmacological relevance Sophora flavescens is a traditional Chinese medicine
commonly used in clinical practice, which has the effects of clearing away heat and …

Sophora flavescens Ait. has been utilized as an anticarcinogen, antibacterial and
insecticide. Two new prenylflavonoids, Sophoflavonoid A (1) and Sophoflavonoid B (2) …

The quinolizidine alkaloids matrine and its N-oxide oxymatrine occur in plants of the genus
Sophora. Recently, matrine was sporadically detected in liquorice products. Morphological …

Three new matrine‐type alkaloids, 8β‐hydroxyoxysophoridine (1), 9β‐hydroxysophoridine
(2), 9β‐hydroxyisosophocarpine (3), together with one known analog, 11, 12 …