Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an
immunoglobulin E (IgE)-mediated inflammation of the membranes lining the nose (1). It was …

The health impacts of tackling fuel poverty are reviewed, drawing primarily on large-scale
studies completed in the last 10 years. Although physical health effects on adults appear to …

Background Benralizumab is a humanised, afucosylated, anti-interleukin-5 receptor α
monoclonal antibody that induces direct, rapid, and nearly complete depletion of …

Background Eosinophilia is associated with worsening asthma severity and decreased lung
function, with increased exacerbation frequency. We assessed the safety and efficacy of …

Introduction In a subset of patients with asthma, standard-of-care treatment does not achieve
disease control, highlighting the need for novel therapeutic approaches. Lebrikizumab is a …

Background: The assessment of asthma control is pivotal to the evaluation of treatment
response in individuals and in clinical trials. Previously, asthma control, severity, and …

Background Asthma is characterized pathologically by structural changes in the airway,
termed airway remodeling. These changes are associated with worse long-term clinical …

Background Investigations meeting current standards are limited for the effect of house dust
mite (HDM) allergy immunotherapy in asthmatic patients. Objective This trial investigated the …

Background Asthma is a chronic inflammatory disease involving diverse cells and mediators
whose interconnectivity and relationships to asthma severity are unclear. Objective We …

Background Disease heterogeneity in patients with severe asthma and its relationship to
inflammatory mechanisms remain poorly understood. Objective We aimed to identify and …