Challenges to the central nervous system during human spaceflight missions to Mars

GR Clément, RD Boyle, KA George… - Journal of …, 2020 - journals.physiology.org
Space travel presents a number of environmental challenges to the central nervous system,
including changes in gravitational acceleration that alter the terrestrial synergies between …

Advances in space radiation physics and transport at NASA

JW Norbury, TC Slaba, S Aghara, FF Badavi… - Life Sciences in Space …, 2019 - Elsevier
The space radiation environment is a complex mixture of particle types and energies
originating from sources inside and outside of the galaxy. These environments may be …

NASA's first ground-based Galactic Cosmic Ray Simulator: Enabling a new era in space radiobiology research

LC Simonsen, TC Slaba, P Guida, A Rusek - PLoS biology, 2020 - journals.plos.org
With exciting new NASA plans for a sustainable return to the moon, astronauts will once
again leave Earth's protective magnetosphere only to endure higher levels of radiation from …

Galactic cosmic ray simulation at the NASA Space Radiation Laboratory

JW Norbury, W Schimmerling, TC Slaba… - Life sciences in space …, 2016 - Elsevier
Most accelerator-based space radiation experiments have been performed with single ion
beams at fixed energies. However, the space radiation environment consists of a wide …

Overview of the NASA space radiation laboratory

C La Tessa, M Sivertz, IH Chiang, D Lowenstein… - Life sciences in space …, 2016 - Elsevier
Abstract The NASA Space Radiation Laboratory (NSRL) is a multidisciplinary center for
space radiation research funded by NASA and located at the Brookhaven National …

A million persons, a million dreams: a vision for a national center of radiation epidemiology and biology

JD Boice, B Quinn, I Al-Nabulsi, A Ansari… - The Million Person …, 2024 - taylorfrancis.com
Background: Epidemiologic studies of radiation-exposed populations form the basis for
human safety standards. They also help shape public health policy and evidence-based …

Mortality among workers at the Los Alamos National laboratory, 1943–2017

JD Boice, SS Cohen, MT Mumma… - The Million Person …, 2024 - taylorfrancis.com
Background: During World War II (WWII), the Manhattan Engineering District established a
secret laboratory in the mountains of northern New Mexico. The mission was to design …

National effort to re-establish heavy ion cancer therapy in the United States

A Pompos, RL Foote, AC Koong, QT Le… - Frontiers in …, 2022 - frontiersin.org
In this review, we attempt to make a case for the establishment of a limited number of heavy
ion cancer research and treatment facilities in the United States. Based on the basic physics …

Progressive increase in the complexity and translatability of rodent testing to assess space-radiation induced cognitive impairment

RA Britten, LL Wellman, LD Sanford - Neuroscience & Biobehavioral …, 2021 - Elsevier
Ground-based rodent models have established that space radiation doses (approximately
those that astronauts will be exposed to on a mission to Mars) significantly impair …

Galactic cosmic ray simulation at the NASA space radiation laboratory–Progress, challenges and recommendations on mixed-field effects

JL Huff, F Poignant, S Rahmanian, N Khan… - Life Sciences in Space …, 2023 - Elsevier
For missions beyond low Earth orbit to the moon or Mars, space explorers will encounter a
complex radiation field composed of various ion species with a broad range of energies …