The eternal or ultimate goal of medicinal chemistry is to find most effective ways to treat
various diseases and extend human beings' life as long as possible. Human being is a …

With the avalanche of protein sequences generated in the post-genomic age, it is highly
desired to develop automated methods for efficiently identifying various attributes of …

One of the fundamental goals in proteomics and cell biology is to identify the functions of
proteins in various cellular organelles and pathways. Information of subcellular locations of …

Information of subcellular locations of proteins is important for in-depth studies of cell
biology. It is very useful for proteomics, system biology and drug development as well …

Predicting protein subcellular localization is an important and difficult problem, particularly
when query proteins may have the multiplex character, ie, simultaneously exist at, or move …

Background Study of drug-target interaction networks is an important topic for drug
development. It is both time-consuming and costly to determine compound-protein …

There are different types of cyclins, which are active during the cell cycle and enable cyclin-
dependent kinases to phosphorylate different substrates. Since there is not much similarity …

Using graphic rules to deal with kinetic systems is an elegant approach by combining the
graph representation (schematic representation) and rigorous mathematical derivation. It …

Protein secondary structure carries information about local structural arrangements.
Significant majority of successful methods for predicting the secondary structure is based on …

By incorporating the information of gene ontology, functional domain, and sequential
evolution, a new predictor called Gneg-mPLoc was developed. It can be used to identify …