Simple Summary Osteosarcoma is the most common malignant bone tumor in children, with
a 5-year survival rate ranging from 70% to 20% depending on the aggressiveness of the …

Osteosarcoma is a rare primary bone cancer characterized by cancer cells producing
calcified osteoid extracellular matrix and inducing lung metastases with a high frequency …

Necrotic bone exposure in the oral cavity has recently been reported in patients treated with
nitrogen‐containing bisphosphonates as part of their therapeutic regimen for multiple …

BACKGROUND: This study evaluated the safety and feasibility of the addition of
pamidronate to chemotherapy for treatment of osteosarcoma. METHODS: The authors …

Osteosarcoma is the most common primary malignant tumor of the skeleton in teenagers
and young adults and continues to confer a generally poor prognosis in patients who do not …

Osteosarcoma (OS) is a high-grade malignant stromal tumor composed of mesenchymal
cells producing osteoid and immature bone, with a peak of incidence in the second decade …

Bone sarcomas are primary bone tumours found mainly in children and adolescents, as
osteosarcoma and Ewing's sarcoma, and in adults in their 40s as chondrosarcoma. The last …

Advanced, recurrent, or metastasized osteosarcomas remain challenging to cure or even
alleviate. Therefore, the development of novel therapeutic strategies is urgently needed …

Even though combining surgery with chemotherapy has significantly improved the prognosis
of osteosarcoma patients, advanced, metastatic, or recurrent osteosarcomas are often non …

Osteosarcoma (OS) is the most common non-hematologic malignant tumor of bone in adults
and children. As sarcomas are more common in adolescents and young adults than most …