Nanoparticles (NPs) have emerged as an effective modality for the treatment of various
diseases including cancer, cardiovascular and inflammatory diseases. Various forms of NPs …

Microneedles have been used for the dermal and transdermal delivery of a broad range of
drugs, such as small molecular weight drugs, oligonucleotides, DNA, peptides, proteins and …

The progress in microneedle research is evidenced by the transition from simple 'poke and
patch'solid microneedles fabricated from silicon and stainless steel to the development of …

Objectives One of the thrust areas in drug delivery research is transdermal drug delivery
systems (TDDS) due to their characteristic advantages over oral and parenteral drug …

The treatment and prevention of infectious diseases is a major part of both clinical and
investigative medicine. As the use of conventional antibiotics rises, antimicrobial resistance …

Subunit vaccines offer a safer alternative to traditional organism-based vaccines, but their
immunogenicity is impaired. This hurdle might be overcome by the use of micro-and …

Protein instability and immunogenicity are two main roadblocks to the clinical success of
novel protein drug delivery systems. In this commentary, we discuss the need for more …

Abstract N, N, N-trimethyl chitosan (TMC), a quaternized hydrophilic derivative of chitosan
(CHT), outperformed the well-known solubility issues raised by CHT. The excellent …

Transcutaneous immunization (TCI) is a promising alternative to vaccine delivery via the
subcutaneous and intramuscular routes, due to the unique immunological characteristics of …

Nasal vaccination is a promising, needle-free alternative to classical vaccination.
Nanoparticulate delivery systems have been reported to overcome the poor immunogenicity …