Depression, anxiety, and apathy in Parkinson's disease: insights from neuroimaging studies

MC Wen, LL Chan, LCS Tan… - European journal of …, 2016 - Wiley Online Library
Depression, anxiety and apathy are common mood disturbances in Parkinson's disease
(PD) but their pathophysiology is unclear. Advanced neuroimaging has been increasingly …

Uncovering the role of the insula in non-motor symptoms of Parkinson's disease

L Christopher, Y Koshimori, AE Lang, M Criaud… - Brain, 2014 - academic.oup.com
Patients with Parkinson's disease experience a range of non-motor symptoms, including
cognitive impairment, behavioural changes, somatosensory and autonomic disturbances …

Apathy in Parkinson's disease is associated with nucleus accumbens atrophy: a magnetic resonance imaging shape analysis

N Carriere, P Besson, K Dujardin… - Movement …, 2014 - Wiley Online Library
Apathy is characterized by lack of interest, loss of initiative, and flattening of affect. It is a
frequent, very disabling nonmotor complication of Parkinson's disease (PD). The condition …

[HTML][HTML] Imaging the etiology of apathy, anxiety, and depression in Parkinson's disease: implication for treatment

S Thobois, S Prange, V Sgambato-Faure… - Current neurology and …, 2017 - Springer
Apathy, depression, and anxiety are among the most important non-motor signs of
Parkinson's disease (PD). This may be encountered at early stages of illness and represent …

[图书][B] Neuropsychology: From theory to practice

D Andrewes - 2015 - taylorfrancis.com
The second edition of this comprehensive textbook for students of Neuropsychology gives a
thorough overview of the complex relationship between brain and behaviour. With an …

Cognitive and neuroanatomical correlates of neuropsychiatric symptoms in Parkinson's disease: a systematic review

H Alzahrani, A Venneri - Journal of the neurological sciences, 2015 - Elsevier
Introduction Neuropsychiatric symptoms are one of the most common non-motor symptoms
in Parkinson's disease (PD). These symptoms have a negative impact on daily living …

[HTML][HTML] Neural correlates for apathy: frontal-prefrontal and parietal cortical-subcortical circuits

R Moretti, R Signori - Frontiers in aging neuroscience, 2016 - frontiersin.org
Apathy is an uncertain nosographical entity, which includes reduced motivation, abulia,
decreased empathy, and lack of emotional involvement; it is an important and heavy-burden …

Neural correlates of apathy in patients with neurodegenerative disorders, acquired brain injury, and psychiatric disorders

C Kos, MJ van Tol, JBC Marsman, H Knegtering… - Neuroscience & …, 2016 - Elsevier
Apathy can be described as a loss of goal-directed purposeful behavior and is common in a
variety of neurological and psychiatric disorders. Although previous studies investigated …

Early limbic microstructural alterations in apathy and depression in de novo Parkinson's disease

S Prange, E Metereau, A Maillet… - Movement …, 2019 - Wiley Online Library
Background Whether structural alterations underpin apathy and depression in de novo
parkinsonian patients is unknown. The objectives of this study were to investigate whether …

Emotional manifestations of PD: Neurobiological basis

A Castrioto, S Thobois, S Carnicella… - Movement …, 2016 - Wiley Online Library
Neuropsychiatric symptoms are common and disabling in PD. Their neurobiological bases
are complex, partly because of the disease itself and partly because of the dopaminergic …