Machine learning in onco-pharmacogenomics: A path to precision medicine with many challenges
A Mondello, M Dal Bo, G Toffoli… - Frontiers in Pharmacology, 2024 - frontiersin.org
Over the past two decades, Next-Generation Sequencing (NGS) has revolutionized the
approach to cancer research. Applications of NGS include the identification of tumor specific …
approach to cancer research. Applications of NGS include the identification of tumor specific …
Challenges and Future Directions in the Management of Tumor Mutational Burden-High (TMB-H) Advanced Solid Malignancies
Simple Summary When employing a high tumor mutational burden (TMB) as a predictive
biomarker for immune checkpoint inhibitor (ICI) response, one faces various challenges. It is …
biomarker for immune checkpoint inhibitor (ICI) response, one faces various challenges. It is …
An" alert state" ribosome population acts as a master regulator of cytokine mediated processes
Inflammatory cytokines are pivotal to immune responses. Upon cytokine exposure, cells
enter an'alert-state'that enhances their visibility to the immune system. Here, we identified …
enter an'alert-state'that enhances their visibility to the immune system. Here, we identified …