The limbic system describes a complex of brain structures central for memory, learning, as
well as goal directed and emotional behavior. In addition to pathological studies, recent …

Synucleinopathies are neurodegenerative disorders characterized by alpha-synuclein
(αSyn) accumulation in neurons or glial cells, including Parkinson's disease (PD), dementia …

Cognitive disorders are increasingly recognized in Parkinson disease (PD), even in early
disease stages, and memory is one of the most affected cognitive domains. Classically …

Neuroimaging studies suggest a pivotal role of amygdala dysfunction in non-motor
symptoms (NMS) of Parkinson's disease (PD). However, the relationship between amygdala …

Objective Anxiety is one of the most common psychiatric symptoms of Parkinson's disease
(PD), and brain iron deposition is considered to be one of the pathological mechanisms of …

Objective To identify markers of Parkinson's disease (PD) related anxiety, using high density
electroencephalography (hd-EEG). Methods 108 patients participated in the study. They …

Different psychopathological manifestations, such as affective, psychotic, obsessive-
compulsive symptoms, and impulse control disturbances, may occur in most central nervous …

Background Parkinson's disease (PD) can present with neuropsychiatric symptoms (here,
anxiety, depression, and apathy) at any stage of the disease. We investigated the neural …

While cognitive impairment, which was previously considered a red flag against the clinical
diagnosis of multiple system atrophy (MSA), is a common symptom of this rare …

Objective Anxiety is a prominent concern in Parkinson's disease (PD) that negatively
impacts quality of life, increases functional disability, and complicates clinical management …