Adverse effects of proton pump inhibitors—evidence and plausibility

R Fossmark, TC Martinsen, HL Waldum - International journal of …, 2019 - mdpi.com
Proton pump inhibitors (PPIs) have been increasingly used over the last decades and there
are concerns about overuse and the numerous reported side-effects. It is uncertain whether …

Adverse effects of long-term proton pump inhibitor therapy

E Sheen, G Triadafilopoulos - Digestive diseases and sciences, 2011 - Springer
Proton pump inhibitors have an excellent safety profile and have become one of the most
commonly prescribed class of drugs in primary and specialty care. Long-term, sometimes …

[HTML][HTML] Safety of the long-term use of proton pump inhibitors

ABR Thomson, MD Sauve, N Kassam… - World journal of …, 2010 - ncbi.nlm.nih.gov
The proton pump inhibitors (PPIs) as a class are remarkably safe and effective for persons
with peptic ulcer disorders. Serious adverse events are extremely rare for PPIs, with case …

The current spectrum of gastric polyps: a 1-year national study of over 120,000 patients

SW Carmack, RM Genta, CM Schuler… - Official journal of the …, 2009 - journals.lww.com
OBJECTIVES: To use a large pathology database (Caris Diagnostics) to analyze the
frequency and associations of gastric polyps in a nationwide US population. METHODS: A …

The management of gastric polyps

AF Goddard, R Badreldin, DM Pritchard, MM Walker… - Gut, 2010 - gut.bmj.com
Background Gastric polyps are important as some have malignant potential. If such polyps
are left untreated, gastric cancer may result. The malignant potential depends on the …

Increased risk of fundic gland polyps during long‐term proton pump inhibitor therapy

M Jalving, JJ Koornstra, J Wesseling… - Alimentary …, 2006 - Wiley Online Library
Background It is controversial whether proton pump inhibitor use leads to fundic gland polyp
development. Aim To determine whether fundic gland polyp development is due to proton …

Management of gastric polyps: a pathology-based guide for gastroenterologists

SW Carmack, RM Genta, DY Graham… - Nature Reviews …, 2009 - nature.com
4% of patients who undergo gastric biopsy have gastric polyps. These lesions may be true
epithelial polyps, heterotopias, lymphoid tissue, or stromal lesions. Hyperplastic polyps …

the long‐term use of proton‐pump inhibitors

AS Raghunath, C O'morain… - Alimentary …, 2005 - Wiley Online Library
More than 15 years after the launch of omeprazole in 1988, proton‐pump inhibitors remain
central to the management of acid‐suppression disorders and are unchallenged with regard …

Pathological effects of drugs on the gastrointestinal tract: a review

JR Parfitt, DK Driman - Human pathology, 2007 - Elsevier
Drug-induced injury of the gastrointestinal (GI) tract is increasingly common but generally
under-recognized. Although there is an overwhelming number of drugs that are associated …

[HTML][HTML] Proton pump inhibitor-related gastric mucosal changes

GH Kim - Gut and liver, 2021 - ncbi.nlm.nih.gov
Proton pump inhibitors (PPIs) are used worldwide to treat of acid-related disorders such as
peptic ulcer and gastroesophageal reflux disease and to prevent gastroduodenal injuries …