Bioprocessing in the digital age: the role of process models
In this age of technology, the vision of manufacturing industries built of smart factories is not
a farfetched future. As a prerequisite for Industry 4.0, industrial sectors are moving towards …
a farfetched future. As a prerequisite for Industry 4.0, industrial sectors are moving towards …
Comprehensive review on agricultural waste utilization and high-temperature fermentation and composting
Due to the high demand for food and meat for the world's growing population, the
agricultural sector is expanding every year. Timely and effective treatment is of utmost …
agricultural sector is expanding every year. Timely and effective treatment is of utmost …
Micromixing within microfluidic devices
Micromixing is a crucial process within microfluidic systems such as micro total analysis
systems (μTAS). A state-of-art review on microstructured mixing devices and their mixing …
systems (μTAS). A state-of-art review on microstructured mixing devices and their mixing …
Current state and recent advances in biopharmaceutical production in Escherichia coli, yeasts and mammalian cells
A Berlec, B Štrukelj - Journal of industrial microbiology and …, 2013 - academic.oup.com
Almost all of the 200 or so approved biopharmaceuticals have been produced in one of
three host systems: the bacterium Escherichia coli, yeasts (Saccharomyces cerevisiae …
three host systems: the bacterium Escherichia coli, yeasts (Saccharomyces cerevisiae …
Integration and application of optical chemical sensors in microbioreactors
P Gruber, MPC Marques, N Szita, T Mayr - Lab on a Chip, 2017 - pubs.rsc.org
The quantification of key variables such as oxygen, pH, carbon dioxide, glucose, and
temperature provides essential information for biological and biotechnological applications …
temperature provides essential information for biological and biotechnological applications …
A review of advanced small‐scale parallel bioreactor technology for accelerated process development: Current state and future need
R Bareither, D Pollard - Biotechnology progress, 2011 - Wiley Online Library
The pharmaceutical and biotech industries face continued pressure to reduce development
costs and accelerate process development. This challenge occurs alongside the need for …
costs and accelerate process development. This challenge occurs alongside the need for …
Scale-down simulators for metabolic analysis of large-scale bioprocesses
P Neubauer, S Junne - Current opinion in biotechnology, 2010 - Elsevier
Analytical approaches for a comprehensive understanding of the metabolic networks in
microbial cultures are mostly based on small-scale cultures which are in a steady state or …
microbial cultures are mostly based on small-scale cultures which are in a steady state or …
Novel mutagenesis and screening technologies for food microorganisms: advances and prospects
Q Yu, Y Li, B Wu, W Hu, M He, G Hu - Applied microbiology and …, 2020 - Springer
Microorganisms are indispensable in the food industry, but wild-type strains hardly meet the
current industrial demands due to several undesirable traits. Therefore, microbial strain …
current industrial demands due to several undesirable traits. Therefore, microbial strain …
Experimental methods and modeling techniques for description of cell population heterogeneity
RL Fernandes, M Nierychlo, L Lundin… - Biotechnology …, 2011 - Elsevier
With the continuous development, in the last decades, of analytical techniques providing
complex information at single cell level, the study of cell heterogeneity has been the focus of …
complex information at single cell level, the study of cell heterogeneity has been the focus of …
The development and application of high throughput cultivation technology in bioprocess development
Q Long, X Liu, Y Yang, L Li, L Harvey, B McNeil… - Journal of …, 2014 - Elsevier
This review focuses on recent progress in the technology of high throughput (HTP)
cultivation and its increasing application in quality by design (QbD)-driven bioprocess …
cultivation and its increasing application in quality by design (QbD)-driven bioprocess …