Cancer cachexia: molecular mechanisms and treatment strategies

T Setiawan, IN Sari, YT Wijaya, NM Julianto… - Journal of Hematology & …, 2023 - Springer
Muscle wasting is a consequence of physiological changes or a pathology characterized by
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …

A review on pharmacological activities and synergistic effect of quercetin with small molecule agents

H Zou, H Ye, R Kamaraj, T Zhang, J Zhang, P Pavek - Phytomedicine, 2021 - Elsevier
Background Quercetin is a natural flavonoid, which widely exists in nature, such as tea,
coffee, apples, and onions. Numerous studies have showed that quercetin has multiple …

Cancer cachexia: its mechanism and clinical significance

H Nishikawa, M Goto, S Fukunishi, A Asai… - International journal of …, 2021 - mdpi.com
The term “cachexia” is derived from the Greek words kakos (bad) and hexis (habit).
Cachexia is a malnutrition associated with chronic diseases such as cancer, chronic heart …

Cancer cachexia and its pathophysiology: links with sarcopenia, anorexia and asthenia

S Peixoto da Silva, JMO Santos… - Journal of cachexia …, 2020 - Wiley Online Library
Cancer cachexia is a multifactorial syndrome characterized by a progressive loss of skeletal
muscle mass, along with adipose tissue wasting, systemic inflammation and other metabolic …

Cancer cachexia: definition, staging, and emerging treatments

J Ni, L Zhang - Cancer management and research, 2020 - Taylor & Francis
Cachexia is a multifactorial disease characterized by weight loss via skeletal muscle and
adipose tissue loss, an imbalance in metabolic regulation, and reduced food intake. It is …

Nausea and vomiting of pregnancy and hyperemesis gravidarum

MS Fejzo, J Trovik, IJ Grooten, K Sridharan… - Nature reviews Disease …, 2019 - nature.com
Nausea and vomiting of pregnancy (NVP) is a common condition that affects as many as
70% of pregnant women. Although no consensus definition is available for hyperemesis …

Weight loss, malnutrition, and cachexia in COVID‐19: facts and numbers

MS Anker, U Landmesser… - Journal of cachexia …, 2021 - Wiley Online Library
Patients with COVID‐19 disease are prone to develop significant weight loss and clinical
cachexia. Three reports with altogether 589 patients that reported on weight loss and …

Progesterone as an anti-inflammatory drug and immunomodulator: new aspects in hormonal regulation of the inflammation

TA Fedotcheva, NI Fedotcheva, NL Shimanovsky - Biomolecules, 2022 - mdpi.com
The specific regulation of inflammatory processes by steroid hormones has been actively
studied in recent years, especially by progesterone (P4) and progestins. The mechanisms of …

Skeletal muscle regeneration with robotic actuation–mediated clearance of neutrophils

BR Seo, CJ Payne, SL McNamara… - Science translational …, 2021 - science.org
Mechanical stimulation (mechanotherapy) can promote skeletal muscle repair, but a lack of
reproducible protocols and mechanistic understanding of the relation between mechanical …

Cancer cachexia: more than skeletal muscle wasting

SF Schmidt, M Rohm, S Herzig, MB Diaz - Trends in cancer, 2018 - cell.com
Cancer cachexia is a multifactorial condition characterized by body weight loss that
negatively affects quality of life and survival of patients with cancer. Despite the clinical …