Wolbachia and the biological control of mosquito‐borne disease

I Iturbe‐Ormaetxe, T Walker, SL O'Neill - EMBO reports, 2011 - embopress.org
Mosquito‐borne diseases such as malaria, dengue fever and filariasis cause an enormous
health burden to people living in tropical and subtropical regions of the world. Despite years …

Beyond insecticides: new thinking on an ancient problem

EA McGraw, SL O'neill - Nature Reviews Microbiology, 2013 - nature.com
Vector-borne disease is one of the greatest contributors to human mortality and morbidity
throughout the tropics. Mosquito-transmitted diseases such as malaria, dengue, yellow fever …

Harnessing mosquito–Wolbachia symbiosis for vector and disease control

K Bourtzis, SL Dobson, Z Xi, JL Rasgon, M Calvitti… - Acta tropica, 2014 - Elsevier
Mosquito species, members of the genera Aedes, Anopheles and Culex, are the major
vectors of human pathogens including protozoa (Plasmodium sp.), filariae and of a variety of …

Field evaluation of the establishment potential of wmelpop Wolbachia in Australia and Vietnam for dengue control

TH Nguyen, HL Nguyen, TY Nguyen, SN Vu, ND Tran… - Parasites & vectors, 2015 - Springer
Abstract Background Introduced Wolbachia bacteria can influence the susceptibility of
Aedes aegypti mosquitoes to arboviral infections as well as having detrimental effects on …

The rich somatic life of Wolbachia

JE Pietri, H DeBruhl, W Sullivan - Microbiologyopen, 2016 - Wiley Online Library
Wolbachia is an intracellular endosymbiont infecting most arthropod and some filarial
nematode species that is vertically transmitted through the maternal lineage. Due to this …

Dengue Virus Infection of the Aedes aegypti Salivary Gland and Chemosensory Apparatus Induces Genes that Modulate Infection and Blood-Feeding Behavior

S Sim, JL Ramirez, G Dimopoulos - PLoS pathogens, 2012 - journals.plos.org
The female Aedes aegypti salivary gland plays a pivotal role in bloodmeal acquisition and
reproduction, and thereby dengue virus (DENV) transmission. It produces numerous …

Wolbachia uses host microRNAs to manipulate host gene expression and facilitate colonization of the dengue vector Aedes aegypti

M Hussain, FD Frentiu, LA Moreira… - Proceedings of the …, 2011 - National Acad Sciences
The obligate endosymbiont Wolbachia pipientis is found in a wide range of invertebrates
where they are best known for manipulating host reproduction. Recent studies have shown …

Wolbachia: more than just a bug in insects genitals

A Saridaki, K Bourtzis - Current opinion in microbiology, 2010 - Elsevier
Research on the intracellular bacterial symbiont Wolbachia has grown on many levels,
providing interesting insights on various aspects of the microbe's biology. Although data …

Dynamics of the “Popcorn” Wolbachia Infection in Outbred Aedes aegypti Informs Prospects for Mosquito Vector Control

HL Yeap, P Mee, T Walker, AR Weeks, SL O'Neill… - Genetics, 2011 - academic.oup.com
Forty percent of the world's population is at risk of contracting dengue virus, which produces
dengue fever with a potentially fatal hemorrhagic form. The w MelPop Wolbachia infection of …

Wolbachia Infection Reduces Blood-Feeding Success in the Dengue Fever Mosquito, Aedes aegypti

AP Turley, LA Moreira, SL O'Neill… - PLoS Neglected …, 2009 - journals.plos.org
Background The mosquito Aedes aegypti was recently transinfected with a life-shortening
strain of the endosymbiont Wolbachia pipientis (w MelPop) as the first step in developing a …