Artificial intelligence and advanced melanoma: treatment management implications

A Guerrisi, I Falcone, F Valenti, M Rao, E Gallo… - Cells, 2022 - mdpi.com
Artificial intelligence (AI), a field of research in which computers are applied to mimic
humans, is continuously expanding and influencing many aspects of our lives. From electric …

[HTML][HTML] Imaging to predict checkpoint inhibitor outcomes in cancer. A systematic review

LS Ter Maat, IAJ van Duin, SG Elias… - European Journal of …, 2022 - Elsevier
Background Checkpoint inhibition has radically improved the perspective for patients with
metastatic cancer, but predicting who will not respond with high certainty remains difficult …

Early readout on overall survival of patients with melanoma treated with immunotherapy using a novel imaging analysis

L Dercle, B Zhao, M Gönen, CS Moskowitz… - JAMA …, 2022 - jamanetwork.com
Importance Existing criteria to estimate the benefit of a therapy in patients with cancer rely
almost exclusively on tumor size, an approach that was not designed to estimate survival …

Precision medicine and melanoma: multi-omics approaches to monitoring the immunotherapy response

F Valenti, I Falcone, S Ungania, F Desiderio… - International journal of …, 2021 - mdpi.com
The treatment and management of patients with metastatic melanoma have evolved
considerably in the “era” of personalized medicine. Melanoma was one of the first solid …

CT based radiomic approach on first line pembrolizumab in lung cancer

M Zerunian, D Caruso, A Zucchelli, M Polici… - Scientific Reports, 2021 - nature.com
Clinical evaluation poorly predicts outcomes in lung cancer treated with immunotherapy.
The aim of the study is to assess whether CT-derived texture parameters can predict overall …

Exploring CT texture parameters as predictive and response imaging biomarkers of survival in patients with metastatic melanoma treated with PD-1 inhibitor …

A Guerrisi, M Russillo, E Loi, B Ganeshan… - Frontiers in …, 2021 - frontiersin.org
In the era of artificial intelligence and precision medicine, the use of quantitative imaging
methodological approaches could improve the cancer patient's therapeutic approaches …

Combination of whole-body baseline ct radiomics and clinical parameters to predict response and survival in a stage-iv melanoma cohort undergoing immunotherapy

F Peisen, A Hänsch, A Hering, AS Brendlin, S Afat… - Cancers, 2022 - mdpi.com
Simple Summary The use of immunotherapeutic agents significantly improved stage-IV
melanoma patients' overall progression-free survival. To identify patients who do not benefit …

Assessing immunotherapy with functional and molecular imaging and radiomics

R García-Figueiras, S Baleato-González, A Luna… - Radiographics, 2020 - pubs.rsna.org
Immunotherapy is changing the treatment paradigm for cancer and has introduced new
challenges in medical imaging. Because not all patients benefit from immunotherapy …

FDG PET biomarkers for prediction of survival in metastatic melanoma prior to anti-PD1 immunotherapy

A Flaus, V Habouzit, N De Leiris, JP Vuillez… - Scientific reports, 2021 - nature.com
Our aim was to analyse whether biomarkers extracted from baseline 18F-FDG PET before
anti-PD1 treatment contribute to prognostic survival information for early risk stratification in …

[HTML][HTML] Can delta radiomics improve the prediction of best overall response, progression-free survival, and overall survival of melanoma patients treated with immune …

F Peisen, A Gerken, A Hering, I Dahm, K Nikolaou… - Cancers, 2024 - mdpi.com
Simple Summary The incidence of metastatic melanoma is rising, making it imperative to
identify patients who do not benefit from immunotherapy. This study aimed to develop a …