[HTML][HTML] Resting-state network dysfunction in Alzheimer's disease: a systematic review and meta-analysis
Introduction We performed a systematic review and meta-analysis of the Alzheimer's
disease (AD) literature to examine consistency of functional connectivity alterations in AD …
disease (AD) literature to examine consistency of functional connectivity alterations in AD …
Cell–cell communication inference and analysis in the tumour microenvironments from single-cell transcriptomics: data resources and computational strategies
Carcinomas are complex ecosystems composed of cancer, stromal and immune cells.
Communication between these cells and their microenvironments induces cancer …
Communication between these cells and their microenvironments induces cancer …
Ancestry-inclusive dog genomics challenges popular breed stereotypes
Behavioral genetics in dogs has focused on modern breeds, which are isolated subgroups
with distinctive physical and, purportedly, behavioral characteristics. We interrogated breed …
with distinctive physical and, purportedly, behavioral characteristics. We interrogated breed …
[HTML][HTML] Active eosinophils regulate host defence and immune responses in colitis
In the past decade, single-cell transcriptomics has helped to uncover new cell types and
states and led to the construction of a cellular compendium of health and disease. Despite …
states and led to the construction of a cellular compendium of health and disease. Despite …
NetCoMi: network construction and comparison for microbiome data in R
Motivation Estimating microbial association networks from high-throughput sequencing data
is a common exploratory data analysis approach aiming at understanding the complex …
is a common exploratory data analysis approach aiming at understanding the complex …
[HTML][HTML] Single-cell RNA sequencing reveals evolution of immune landscape during glioblastoma progression
Glioblastoma (GBM) is an incurable primary malignant brain cancer hallmarked with a
substantial protumorigenic immune component. Knowledge of the GBM immune …
substantial protumorigenic immune component. Knowledge of the GBM immune …
[HTML][HTML] A comprehensive subcellular atlas of the Toxoplasma proteome via hyperLOPIT provides spatial context for protein functions
Apicomplexan parasites cause major human disease and food insecurity. They owe their
considerable success to highly specialized cell compartments and structures. These …
considerable success to highly specialized cell compartments and structures. These …
[HTML][HTML] EmptyDrops: distinguishing cells from empty droplets in droplet-based single-cell RNA sequencing data
Droplet-based single-cell RNA sequencing protocols have dramatically increased the
throughput of single-cell transcriptomics studies. A key computational challenge when …
throughput of single-cell transcriptomics studies. A key computational challenge when …
[HTML][HTML] The effect of 16S rRNA region choice on bacterial community metabarcoding results
YS Bukin, YP Galachyants, IV Morozov, SV Bukin… - Scientific data, 2019 - nature.com
In this work, we compare the resolution of V2-V3 and V3-V4 16S rRNA regions for the
purposes of estimating microbial community diversity using paired-end Illumina MiSeq …
purposes of estimating microbial community diversity using paired-end Illumina MiSeq …
[HTML][HTML] A step-by-step workflow for low-level analysis of single-cell RNA-seq data with Bioconductor
Single-cell RNA sequencing (scRNA-seq) is widely used to profile the transcriptome of
individual cells. This provides biological resolution that cannot be matched by bulk RNA …
individual cells. This provides biological resolution that cannot be matched by bulk RNA …