[HTML][HTML] Oral drug delivery strategies for development of poorly water soluble drugs in paediatric patient population

S Salunke, F O'Brien, DCT Tan, D Harris… - Advanced Drug Delivery …, 2022 - Elsevier
Selecting the appropriate formulation and solubility-enabling technology for poorly water
soluble drugs is an essential element in the development of formulations for paediatric …

Patient centric pharmaceutical drug product design—The impact on medication adherence

E Menditto, V Orlando, G De Rosa, P Minghetti… - Pharmaceutics, 2020 - mdpi.com
Medication adherence is a growing concern for public health and poor adherence to therapy
has been associated with poor health outcomes and higher costs for patients. Interventions …

[HTML][HTML] I spy with my little eye: a paediatric visual preferences survey of 3D printed tablets

P Januskaite, X Xu, SR Ranmal, S Gaisford, AW Basit… - Pharmaceutics, 2020 - mdpi.com
3D printing (3DP) in the pharmaceutical field is a disruptive technology that allows the
preparation of personalised medicines at the point of dispensing. The paediatric population …

Orodispersible dosage forms: Biopharmaceutical improvements and regulatory requirements

F Cilurzo, UM Musazzi, S Franzé, F Selmin… - Drug discovery today, 2018 - Elsevier
Highlights•Orodisperisible dosage forms improve the patient's compliance and/or
adherence.•Bioavailability must take in consideration the possible pre-gastric …

Embedded 3D printing of novel bespoke soft dosage form concept for pediatrics

K Rycerz, KA Stepien, M Czapiewska, BT Arafat… - Pharmaceutics, 2019 - mdpi.com
Embedded three-dimensional printing (e-3DP) is an emerging method for additive
manufacturing where semi-solid materials are extruded within a solidifying liquid matrix …

Patient acceptability, safety and access: A balancing act for selecting age-appropriate oral dosage forms for paediatric and geriatric populations

J Walsh, SR Ranmal, TB Ernest, F Liu - International journal of …, 2018 - Elsevier
The selection and design of age-appropriate formulations intended for use in paediatric and
geriatric patients are dependent on multiple factors affecting patient acceptability, safety and …

Solid dispersion formulations by FDM 3D printing—A review

GM Khalid, N Billa - Pharmaceutics, 2022 - mdpi.com
Additive manufacturing (AM) is revolutionizing the way medicines are designed,
manufactured, and utilized. Perhaps, AM appears to be ideal for the fit-for-purpose …

Children's preferences for oral dosage forms and their involvement in formulation research via EPTRI (European Paediatric Translational Research Infrastructure)

E Alessandrini, F Brako, M Scarpa, M Lupo, D Bonifazi… - Pharmaceutics, 2021 - mdpi.com
The paucity of evidence-based data on formulation characteristics preferred by the children
is known to limit the design of tailored paediatric dosage forms. The European Paediatric …

Individualized orodispersible pediatric dosage forms obtained by molding and semi-solid extrusion by 3D printing: A comparative study for hydrochlorothiazide

J Suárez-González, M Magariños-Triviño… - Journal of Drug Delivery …, 2021 - Elsevier
Orodispersible tablets are an excellent alternative regarding drug administration in pediatric
patients. Nowadays there are alternatives to the compression process including; molding …

Colour of medicines and children's acceptability? A systematic literature review of children's perceptions about colours of oral dosage forms

E Alessandrini, M Gonakova, H Batchelor… - Pharmaceutics, 2023 - mdpi.com
The colour of a product plays an important role in consumer experiences, and in the context
of pharmaceutical products, this could potentially affect a patient's expectations, behaviours …