Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention
owing to their capability of achieving exquisite control over drug release via the exposure to …

Targeted drug delivery refers to an established therapeutic strategy that develops platforms
and nanoscale devices for selective delivery of small drug molecules and therapeutic genes …

Patients with acute myeloid leukaemia who relapse following therapy have few treatment
options and face poor outcomes. Immune checkpoint inhibition, for example, by antibody …

Recent advances in nanoparticle technology have enabled the fabrication of nanoparticle
classes with unique sizes, shapes and materials, which in turn has facilitated major …

Highly sensitive detection of small, deep tumors for early diagnosis and surgical
interventions remains a challenge for conventional imaging modalities. Second-window …

Interfacial multivalent interactions at pathogen–cell interfaces can be competitively inhibited
by multivalent scaffolds that prevent pathogen adhesion to the cells during the initial stages …

Molecular imaging allows clinicians to visualize the progression of tumours and obtain
relevant information for patient diagnosis and treatment. Owing to their intrinsic optical …

To achieve the promise of stimuli-responsive drug delivery systems for the treatment of
cancer, they should (1) avoid premature clearance;(2) accumulate in tumors and undergo …

This book provides basic principles of multivalent interactions found in biological systems as
well as an up-to-date and thorough coverage in design concepts, syntheses, and biological …

Macrophages, the major component of the mononuclear phagocyte system, uptake and
clear systemically administered nanoparticles (NPs). Therefore, leveraging macrophages as …