Skeletal muscle health is a strong predictor of overall health and longevity. Pathologies
affecting skeletal muscle such as cancer cachexia, intensive care unit treatment, muscular …

Depression is a widespread and devastating mental illness and the search for rapid-acting
antidepressants remains critical. There is now exciting evidence that the psychedelic …

Major depressive disorder (MDD) is a common psychiatric illness that manifests in sex-
influenced ways. Men and women may experience depression differently and also respond …

Introduction Sex bias has been an issue in many biomedical fields, especially in
neuroscience. In rodent research, many scientists only focused on male animals due to the …

Men and women often experience different symptoms or rates of occurrence for a variety of
mood disorders. Many of the symptoms of mood disorders overlap with autoimmune …

Depression, the most prevalent psychiatric disorder, is characterized by increased negative
affect (ie depressed mood) and reduced positive affect (ie anhedonia). Stress is a risk factor …

Ketamine is shown to enhance excitatory synaptic drive in multiple brain areas, which is
presumed to underlie its rapid antidepressant effects. Moreover, ketamine's therapeutic …

Inflammation plays a role in depression pathophysiology and treatment response, with
effects varying by sex and therapeutic modality. Lower levels of interleukin (IL)-8 predict …

Major depressive disorder (MDD) is a debilitating disease with a high worldwide prevalence.
Despite its greater prevalence in women, male animals are used in most preclinical studies …

In this review, we will discuss the safety of repeated treatments with ketamine for patients
with treatment-resistant depression (TRD), a condition in which patients with major …