The roles of perineuronal nets and the perinodal extracellular matrix in neuronal function

JW Fawcett, T Oohashi, T Pizzorusso - Nature Reviews Neuroscience, 2019 - nature.com
Perineuronal nets (PNNs) are extracellular matrix (ECM) chondroitin sulfate proteoglycan
(CSPG)-containing structures that surround the soma and dendrites of various mammalian …

New insights into the development of the human cerebral cortex

Z Molnár, GJ Clowry, N Šestan, A Alzu'bi… - Journal of …, 2019 - Wiley Online Library
The cerebral cortex constitutes more than half the volume of the human brain and is
presumed to be responsible for the neuronal computations underlying complex phenomena …

Development and arealization of the cerebral cortex

CR Cadwell, A Bhaduri, MA Mostajo-Radji, MG Keefe… - Neuron, 2019 - cell.com
Adult cortical areas consist of specialized cell types and circuits that support unique higher-
order cognitive functions. How this regional diversity develops from an initially uniform …

Hippocampal GABAergic inhibitory interneurons

KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

Interneuron cell types are fit to function

A Kepecs, G Fishell - Nature, 2014 - nature.com
Understanding brain circuits begins with an appreciation of their component parts—the cells.
Although GABAergic interneurons are a minority population within the brain, they are crucial …

Brain on stress: how the social environment gets under the skin

BS McEwen - Proceedings of the National Academy of …, 2012 - National Acad Sciences
Stress is a state of the mind, involving both brain and body as well as their interactions; it
differs among individuals and reflects not only major life events but also the conflicts and …

Critical periods in speech perception: new directions

JF Werker, TK Hensch - Annual review of psychology, 2015 - annualreviews.org
A continuing debate in language acquisition research is whether there are critical periods
(CPs) in development during which the system is most responsive to environmental input …

Fast-spiking parvalbumin-positive interneurons in brain physiology and Alzheimer's disease

S Hijazi, AB Smit, RE van Kesteren - Molecular Psychiatry, 2023 - nature.com
Fast-spiking parvalbumin (PV) interneurons are inhibitory interneurons with unique
morphological and functional properties that allow them to precisely control local circuitry …

Social influences on neuroplasticity: stress and interventions to promote well-being

RJ Davidson, BS McEwen - Nature neuroscience, 2012 - nature.com
Experiential factors shape the neural circuits underlying social and emotional behavior from
the prenatal period to the end of life. These factors include both incidental influences, such …

Critical period regulation across multiple timescales

RK Reh, BG Dias, CA Nelson III… - Proceedings of the …, 2020 - National Acad Sciences
Brain plasticity is dynamically regulated across the life span, peaking during windows of
early life. Typically assessed in the physiological range of milliseconds (real time), these …