Emerging role of hydrogels in drug delivery systems, tissue engineering and wound management

S Jacob, AB Nair, J Shah, N Sreeharsha, S Gupta… - Pharmaceutics, 2021 - mdpi.com
The popularity of hydrogels as biomaterials lies in their tunable physical properties, ability to
encapsulate small molecules and macromolecular drugs, water holding capacity, flexibility …

Advances in nanoparticulate drug delivery approaches for sublingual and buccal administration

S Hua - Frontiers in pharmacology, 2019 - frontiersin.org
The sublingual and buccal routes of administration have significant advantages for both
local and systemic drug delivery. They have shown to be an effective alternative to the …

An updated overview of the emerging role of patch and film-based buccal delivery systems

S Jacob, AB Nair, SHS Boddu, B Gorain, N Sreeharsha… - Pharmaceutics, 2021 - mdpi.com
Buccal mucosal membrane offers an attractive drug-delivery route to enhance both systemic
and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery …

An overview of polymeric dosage forms in buccal drug delivery: State of art, design of formulations and their in vivo performance evaluation

B Fonseca-Santos, M Chorilli - Materials Science and Engineering: C, 2018 - Elsevier
Owing to the ease of the administration, the oral cavity is an attractive site for the delivery of
drugs. The main difficulty for administration via the buccal route is an effective physiological …

Nanoemulsion based vehicle for effective ocular delivery of moxifloxacin using experimental design and pharmacokinetic study in rabbits

J Shah, AB Nair, S Jacob, RK Patel, H Shah… - Pharmaceutics, 2019 - mdpi.com
Nanoemulsion is one of the potential drug delivery strategies used in topical ocular therapy.
The purpose of this study was to design and optimize a nanoemulsion-based system to …

Nanoparticles in dentistry: A comprehensive review

G Moraes, C Zambom, WL Siqueira - Pharmaceuticals, 2021 - mdpi.com
In recent years, nanoparticles (NPs) have been receiving more attention in dentistry. Their
advantageous physicochemical and biological properties can improve the diagnosis …

[HTML][HTML] Development and optimization of naringenin-loaded chitosan-coated nanoemulsion for topical therapy in wound healing

SH Akrawi, B Gorain, AB Nair, H Choudhury, M Pandey… - Pharmaceutics, 2020 - mdpi.com
The potential role of naringenin (NAR), a natural flavonoid, in the treatment of chronic wound
has prompted the present research to deliver the drug in nanoemulsion (NE) form, where …

Formulation and optimization of sodium alginate polymer film as a buccal mucoadhesive drug delivery system containing cetirizine dihydrochloride

K Pamlényi, K Kristó, O Jójárt-Laczkovich, G Regdon Jr - Pharmaceutics, 2021 - mdpi.com
Currently, pharmaceutical companies are working on innovative methods, processes and
products. Oral mucoadhesive systems, such as tablets, gels, and polymer films, are among …

Development of mucoadhesive buccal film for rizatriptan: In vitro and in vivo evaluation

AB Nair, J Shah, S Jacob, BE Al-Dhubiab, V Patel… - Pharmaceutics, 2021 - mdpi.com
The reduced therapeutic efficacy of rizatriptan in migraine treatment is primarily due to low
oral bioavailability and extensive first pass metabolism. The purpose of this investigation …

Experimental design, formulation and in vivo evaluation of a novel topical in situ gel system to treat ocular infections

AB Nair, J Shah, S Jacob, BE Al-Dhubiab… - PloS one, 2021 - journals.plos.org
In situ gels have been extensively explored as ocular drug delivery system to enhance
bioavailability and efficacy. The objective of present study was to design, formulate and …