Spotlight on microRNAs in allergy and asthma

J Weidner, S Bartel, A Kılıç, UM Zissler, H Renz… - Allergy, 2021 - Wiley Online Library
In past 10 years, microRNAs (miRNAs) have gained scientific attention due to their
importance in the pathophysiology of allergic diseases and their potential as biomarkers in …

Extracellular vesicles: novel communicators in lung diseases

A Mohan, S Agarwal, M Clauss, NS Britt… - Respiratory research, 2020 - Springer
The lung is the organ with the highest vascular density in the human body. It is therefore
perceivable that the endothelium of the lung contributes significantly to the circulation of …

Asthma diagnosis using integrated analysis of eosinophil microRNAs

JM Rodrigo‐Muñoz, JA Cañas, B Sastre, N Rego… - Allergy, 2019 - Wiley Online Library
Background Asthma is a syndrome characterized by airway inflammation and obstruction.
Due to its heterogeneity, the difficulties in asthma diagnosis and treatment make the …

The axis of the receptor for advanced glycation endproducts in asthma and allergic airway disease

TN Perkins, ML Donnell, TD Oury - Allergy, 2021 - Wiley Online Library
Asthma is a generalized term that describes a scope of distinct pathologic phenotypes of
variable severity, which share a common complication of reversible airflow obstruction …

Exosomal microRNA/miRNA Dysregulation in Respiratory Diseases: From Mycoplasma-Induced Respiratory Disease to COVID-19 and Beyond

Y Wang, M Zou, Y Zhao, MA Kabir, X Peng - Cells, 2023 - mdpi.com
Respiratory diseases represent a significant economic and health burden worldwide,
affecting millions of individuals each year in both human and animal populations …

Effects of Dendrimer-microRNA Nanoformulations against Glioblastoma Stem Cells

N Knauer, M Meschaninova, S Muhammad, D Hänggi… - Pharmaceutics, 2023 - mdpi.com
Glioblastoma is a rapidly progressing tumor quite resistant to conventional treatment. These
features are currently assigned to a self-sustaining population of glioblastoma stem cells …

An overview of epigenetic agents and natural nutrition products targeting DNA methyltransferase, histone deacetylases and microRNAs

D Huang, LQ Cui, S Ahmed, F Zainab, Q Wu… - Food and Chemical …, 2019 - Elsevier
Several humans' diseases such as; cancer, heart disease, diabetes retain an etiology of
epigenetic, and a new therapeutic option termed as “epigenetic therapy” can offer a potential …

[HTML][HTML] MicroRNA-21 inhibition suppresses alveolar M2 macrophages in an ovalbumin-induced allergic asthma mice model

HY Lee, J Hur, JY Kang, CK Rhee… - Allergy, Asthma & …, 2021 - ncbi.nlm.nih.gov
Purpose MicroRNA-21 (miR-21) influences the Th2 immune pathway by suppressing the
expressions of interleukin (IL)-12 and interferon (IFN)-γ. The effects of miR-21 suppression …

Non-coding RNA regulation of macrophage function in asthma

C Tian, J Gao, L Yang, X Yuan - Cellular Signalling, 2023 - Elsevier
As a chronic respiratory disease, asthma is related to airway inflammation and remodeling.
Macrophages are regarded as main innate immune cells in the airway that exert various …

A review of macrophage micrornas' role in human asthma

G Feketea, CI Bocsan, C Popescu, M Gaman… - Cells, 2019 - mdpi.com
There is an imbalance in asthma between classically activated macrophages (M1 cells) and
alternatively activated macrophages (M2 cells) in favor of the latter. MicroRNAs (miRNAs) …