While integrins were originally discovered as cell adhesion receptors, recent studies have
reinforced the concept that integrins have central roles in cancer that extend far beyond …

Prostate cancer morbidity and mortality are increasing globally and in China, and the rate of
metastasis is also rising, limiting the therapeutic effect and clinical prognosis of prostate …

Background Bone metastasis is the most common metastatic destination in advanced breast
cancer, presenting a poor prognosis and clinical challenges in management. To date, the …

Platelets are implicated as key players in the metastatic dissemination of tumor cells.
Previous evidence demonstrated platelets retained cytoplasmic RNAs with physiologically …

As one of the most common metastatic sites, bone has a unique microenvironment for the
growth and prosperity of metastatic tumor cells. Bone metastasis is a common complication …

CD151/Tspan24 (SFS-1, PETA3) is one of the best characterized members of the
tetraspanin family, whose involvement in breast cancer (BCa) progression was …

We previously demonstrated that a combination of epigenetic drugs azacitidine (DNA
hypomethylating agent) and panobinostat (HDACi) can sensitize acute lymphoblastic …

Background Bladder carcinoma is the most prevalent malignant tumor involving urinary
system. In 2021, it is the tenth most common cancer worldwide. Various carcinomas showed …

The gastric, hepatic, pancreatic, and colon cancers are major gastrointestinal (GI) tract
cancers account for 50% of all types of cancers with poor 5-year survival rate and high …