Phloretin is a flavonoid of the dihydrogen chalcone class, present abundantly in apples and
strawberries. The beneficial effects of phloretin are mainly associated with its potent …

Difficult or even non-healing diabetic foot ulcers (DFU) are a global medical challenge.
Although current treatments such as debridement, offloading, and infection control have …

Molecular docking revealed curcumin as a potent CB2 cannabinoid receptor (CB2R)
agonist. Since CB2R is involved in cardioprotective functions, we explored its role in …

Diabetes associated oxidative stress and impaired cholinergic neurotransmission causes
cognitive deficits. Although phloridzin shows antioxidant-and insulin sensitizing-activities, its …

The Mediterranean Diet (MedDiet) is associated with beneficial effects against chronic non-
communicable diseases (CNCDs). In particular, the content of micronutrients leads to an …

Oxidative stress is a contributing factor that leads to the vascular complications of diabetes
mellitus. Diabetic peripheral neuropathy (DPN) is one of the microvascular complications …

Ethnopharmacological relevance Sphenocentrum jollyanum whole stem extract is used
traditionally in combination with its leaves to treat chronic wounds and also ameliorate …

Abstract Purpose Type 2 diabetes (T2D) is linked with depression due to insulin resistance,
oxidative stress and disruption of neurotrophic factors. We evaluated potential benefits of …

OBJECTIVE: To evaluate the effects of Zuyangping (足疡平, ZYP) formula on wound healing
in diabetic rats, as well as the molecular mechanisms involved. METHODS: The main …

Plant-based drugs have attracted a lot of attention because of their broad therapeutic
qualities and specificity as medicines, nutraceuticals, and functional foods in human health …