Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …

Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …

Mesenchymal stem cells (MSCs) can be derived from various adult tissues with multipotent
and self‐renewal abilities. The characteristics of presenting no major ethical concerns …

In the recent years, it has been demonstrated that the biological activity of mesenchymal
stem cells (MSCs) is mediated through the release of paracrine factors. Many of these …

Purpose The management of perianal fistula in patients with Crohn's disease is an
extremely challenging medical problem as many fistulas do not respond to available …

In late 2019, a novel coronavirus (SARS-CoV-2) emerged in Wuhan, capital city of Hubei
province in China. Cases of SARS-CoV-2 infection quickly grew by several thousand per …

MSCs products as well as their derived extracellular vesicles, are currently being explored
as advanced biologics in cell-based therapies with high expectations for their clinical use in …

Introduction The ability to self-renew, be easily expanded in vitro and differentiate into
different mesenchymal tissues, render mesenchymal stem cells (MSCs) an attractive …

In 2001, researchers at the University of California, Los Angeles, described the isolation of a
new population of adult stem cells from liposuctioned adipose tissue. These stem cells, now …

Clinical-grade mesenchymal stromal cells (MSCs) are usually expanded from bone marrow
(BMMSCs) or adipose tissue (ADSCs) using processes mainly differing in the use of fetal …