Apoptotic cell recognition receptors and scavenger receptors

KK Penberthy, KS Ravichandran - Immunological reviews, 2016 - Wiley Online Library
Phosphatidylserine recognition receptors are a highly diverse set of receptors grouped by
their ability to recognize the 'eat‐me'signal phosphatidylserine on apoptotic cells. Most of the …

Regulation of T cell responses by the receptor molecule Tim-3

JV Gorman, JD Colgan - Immunologic research, 2014 - Springer
Tim-3 is a member of the T cell immunoglobulin and mucin domain (Tim) family of proteins,
which are expressed by several cell types in the immune system, including CD4 and CD8 T …

[PDF][PDF] TIM-1 ubiquitination mediates dengue virus entry

O Dejarnac, ML Hafirassou, M Chazal, M Versapuech… - Cell reports, 2018 - cell.com
Dengue virus (DENV) is a major human pathogen causing millions of infections yearly.
Despite intensive investigations, a DENV receptor that directly participates in virus …

Phosphatidylserine liposomes mimic apoptotic cells to attenuate atherosclerosis by expanding polyreactive IgM producing B1a lymphocytes

H Hosseini, Y Li, P Kanellakis, C Tay… - Cardiovascular …, 2015 - academic.oup.com
Aims To investigate whether activation of atheroprotective peritoneal B1a cells by apoptotic
cells or phosphatidylserine liposomes (PSLs) can enhance their protective actions during …

Tim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infection

JV Gorman, G Starbeck-Miller, NLL Pham… - The Journal of …, 2014 - journals.aai.org
T cell Ig and mucin domain (Tim) 3 is a surface molecule expressed throughout the immune
system that can mediate both stimulatory and inhibitory effects. Previous studies have …

Characterizing functional domains for TIM-mediated enveloped virus entry

S Moller-Tank, LM Albritton, PD Rennert… - Journal of …, 2014 - Am Soc Microbiol
ABSTRACT T-cell immunoglobulin and mucin domain 1 (TIM-1) and other TIM family
members were recently identified as phosphatidylserine (PtdSer)-mediated virus entry …

Sensing Dying Cells in Health and Disease: The Importance of Kidney Injury Molecule-1

E Tutunea-Fatan, S Arumugarajah… - Journal of the …, 2024 - journals.lww.com
Abstract Kidney Injury Molecule-1 (KIM-1), also known as T cell immunoglobulin and mucin
domain-1 (TIM-1), is a widely recognized biomarker for acute kidney injury, but its biological …

Novel roles for TIM-1 in immunity and infection

PD Rennert - Immunology letters, 2011 - Elsevier
T cell, immunoglobulin domain and mucin domain-1 (TIM-1) is the nominant member of a
small family of related proteins that regulate immune cell activities. TIM-1 was initially …

Src family protein kinase controls the fate of B cells in autoimmune diseases

X Zhang, D Mei, L Zhang, W Wei - Inflammation, 2021 - Springer
There are more than 80 kinds of autoimmune diseases known at present, including
rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), systemic sclerosis (SSc) …

G protein α12 (Gα12) is a negative regulator of kidney injury molecule-1-mediated efferocytosis

OZ Ismail, X Zhang, JV Bonventre… - American Journal of …, 2016 - journals.physiology.org
Kidney injury molecule-1 (KIM-1) is a receptor for the “eat me” signal, phosphatidylserine, on
apoptotic cells. The specific upregulation of KIM-1 by injured tubular epithelial cells (TECs) …