The changing therapeutic landscape of head and neck cancer

JD Cramer, B Burtness, QT Le, RL Ferris - Nature reviews Clinical …, 2019 - nature.com
Head and neck cancers are a heterogeneous collection of malignancies of the upper
aerodigestive tract, salivary glands and thyroid. In this Review, we primarily focus on the …

Head and neck cancer

LQM Chow - New England Journal of Medicine, 2020 - Mass Medical Soc
Head and Neck Cancer Most head and neck cancers (73% in the United States) are now
related to human papillomavirus infection rather than tobacco and alcohol. Primary cancers …

Reduced-dose radiation therapy for HPV-associated oropharyngeal carcinoma (NRG Oncology HN002)

SS Yom, P Torres-Saavedra, JJ Caudell… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Reducing radiation treatment dose could improve the quality of life (QOL) of
patients with good-risk human papillomavirus–associated oropharyngeal squamous cell …

Squamous cell carcinoma of the oral cavity, larynx, oropharynx and hypopharynx: EHNS–ESMO–ESTRO Clinical Practice Guidelines for diagnosis, treatment and …

JP Machiels, CR Leemans, W Golusinski… - Annals of …, 2020 - annalsofoncology.org
Squamous cell carcinoma of the head and neck (SCCHN) arises from epithelial cells and
occurs in the oral cavity, pharynx and larynx. Nasopharyngeal carcinoma (NPC) is a disease …

Weekly cisplatin plus radiation for postoperative head and neck cancer (JCOG1008): a multicenter, noninferiority, phase II/III randomized controlled trial

N Kiyota, M Tahara, J Mizusawa, T Kodaira… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE The standard treatment for postoperative high-risk locally advanced squamous
cell carcinoma of the head and neck (LA-SCCHN) is chemoradiotherapy with 3-weekly …

Treating head and neck cancer in the age of immunotherapy: a 2023 update

A Bhatia, B Burtness - Drugs, 2023 - Springer
Most patients diagnosed with head and neck squamous cell carcinoma (HNSCC) will
present with locally advanced disease, requiring multimodality therapy. While this approach …

Management of the neck in squamous cell carcinoma of the oral cavity and oropharynx: ASCO clinical practice guideline

SA Koyfman, N Ismaila, D Crook, A D'Cruz… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE The aim of the current work is to provide evidence-based recommendations to
practicing physicians and others on the management of the neck in patients with squamous …

Consensuses, controversies, and future directions in treatment deintensification for human papillomavirus‐associated oropharyngeal cancer

JJ Kang, Y Yu, L Chen, K Zakeri… - CA: a cancer journal …, 2023 - Wiley Online Library
The most common cancer caused by human papillomavirus (HPV) infection in the United
States is oropharyngeal cancer (OPC), and its incidence has been rising since the turn of the …

Thyroid hormones and cancer: a comprehensive review of preclinical and clinical studies

E Krashin, A Piekiełko-Witkowska, M Ellis… - Frontiers in …, 2019 - frontiersin.org
Thyroid hormones take major part in normal growth, development and metabolism. Over a
century of research has supported a relationship between thyroid hormones and the …

Diagnosis and management of squamous cell carcinoma of unknown primary in the head and neck: ASCO guideline

E Maghami, N Ismaila, A Alvarez… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE To provide evidence-based recommendations to practicing physicians and other
health care providers on the diagnosis and management of squamous cell carcinoma of …