Three is a crowd–new insights into rosetting in Plasmodium falciparum
XY Yam, M Niang, KG Madnani, PR Preiser - Trends in Parasitology, 2017 - cell.com
The intracellular malaria parasites extensively modify host erythrocytes to allow nutrient
uptake, ensure homeostasis, and evade the host's immune response. To achieve this, the …
uptake, ensure homeostasis, and evade the host's immune response. To achieve this, the …
Recent advances in malaria genomics and epigenomics
Malaria continues to impose a significant disease burden on low-and middle-income
countries in the tropics. However, revolutionary progress over the last 3 years in nucleic acid …
countries in the tropics. However, revolutionary progress over the last 3 years in nucleic acid …
Multispectral atomic force microscopy-infrared nano-imaging of malaria infected red blood cells
Atomic force microscopy-infrared (AFM-IR) spectroscopy is a powerful new technique that
can be applied to study molecular composition of cells and tissues at the nanoscale. AFM-IR …
can be applied to study molecular composition of cells and tissues at the nanoscale. AFM-IR …
The knob protein KAHRP assembles into a ring-shaped structure that underpins virulence complex assembly
O Looker, AJ Blanch, B Liu, J Nunez-Iglesias… - PLoS …, 2019 - journals.plos.org
Plasmodium falciparum mediates adhesion of infected red blood cells (RBCs) to blood
vessel walls by assembling a multi-protein complex at the RBC surface. This virulence …
vessel walls by assembling a multi-protein complex at the RBC surface. This virulence …
Plasmodium falciparum rosetting protects schizonts against artemisinin
Background Artemisinin (ART) resistance in Plasmodium falciparum is thought to occur
during the early stage of the parasite's erythrocytic cycle. Here, we identify a novel factor …
during the early stage of the parasite's erythrocytic cycle. Here, we identify a novel factor …
Modeling cytoadhesion of Plasmodium falciparum‐infected erythrocytes and leukocytes—common principles and distinctive features
Cytoadhesion of Plasmodium falciparum‐infected erythrocytes to the microvascular
endothelial lining shares striking similarities to cytoadhesion of leukocytes. In both cases …
endothelial lining shares striking similarities to cytoadhesion of leukocytes. In both cases …
Structural analysis of P. falciparum KAHRP and PfEMP1 complexes with host erythrocyte spectrin suggests a model for cytoadherent knob protrusions
Plasmodium falciparum Erythrocyte Membrane Protein 1 (Pf EMP1) and Knob-associated
Histidine-rich Protein (KAHRP) are directly linked to malaria pathology. Pf EMP1 and …
Histidine-rich Protein (KAHRP) are directly linked to malaria pathology. Pf EMP1 and …
VAR2CSA-Mediated Host Defense Evasion of Plasmodium falciparum Infected Erythrocytes in Placental Malaria
A Tomlinson, JP Semblat, B Gamain… - Frontiers in …, 2021 - frontiersin.org
Over 30 million women living in P. falciparum endemic areas are at risk of developing
malaria during pregnancy every year. Placental malaria is characterized by massive …
malaria during pregnancy every year. Placental malaria is characterized by massive …
APEX2-based proximity proteomic analysis identifies candidate interactors for Plasmodium falciparum knob-associated histidine-rich protein in infected erythrocytes
The interaction of Plasmodium falciparum—infected red blood cells (iRBCs) with the
vascular endothelium plays a crucial role in malaria pathology and disease. KAHRP is an …
vascular endothelium plays a crucial role in malaria pathology and disease. KAHRP is an …
Evasion of Classical Complement Pathway Activation on Plasmodium falciparum-Infected Erythrocytes Opsonized by PfEMP1-Specific IgG
MD Larsen, MP Quintana, SB Ditlev… - Frontiers in …, 2019 - frontiersin.org
Members of the PfEMP1 protein family are expressed on the surface of P. falciparum-
infected erythrocytes (IEs), where they contribute to the pathogenesis of malaria and are …
infected erythrocytes (IEs), where they contribute to the pathogenesis of malaria and are …