Haptoglobin: From hemoglobin scavenging to human health
A di Masi, G De Simone, C Ciaccio, S D'Orso… - Molecular Aspects of …, 2020 - Elsevier
Haptoglobin (Hp) belongs to the family of acute-phase plasma proteins and represents the
most important plasma detoxifier of hemoglobin (Hb). The basic Hp molecule is a tetrameric …
most important plasma detoxifier of hemoglobin (Hb). The basic Hp molecule is a tetrameric …
[HTML][HTML] Platypus and echidna genomes reveal mammalian biology and evolution
Egg-laying mammals (monotremes) are the only extant mammalian outgroup to therians
(marsupial and eutherian animals) and provide key insights into mammalian evolution 1, 2 …
(marsupial and eutherian animals) and provide key insights into mammalian evolution 1, 2 …
[HTML][HTML] Discovery of all three types in cartilaginous fishes enables phylogenetic resolution of the origins and evolution of interferons
AK Redmond, J Zou, CJ Secombes… - Frontiers in …, 2019 - frontiersin.org
Interferons orchestrate host antiviral responses in jawed vertebrates. They are categorized
into three classes; IFN1 and IFN3 are the primary antiviral cytokine lineages, while IFN2 …
into three classes; IFN1 and IFN3 are the primary antiviral cytokine lineages, while IFN2 …
Horizontal transfer of vertebrate vision gene IRBP into the chordate ancestor
AK Redmond, A McLysaght - Proceedings of the National …, 2023 - National Acad Sciences
Interphotoreceptor retinoid-binding protein (IRBP) plays a key role in vertebrate vision by
transporting retinoids between photoreceptor and retinal pigment epithelium cells in the eye …
transporting retinoids between photoreceptor and retinal pigment epithelium cells in the eye …
[HTML][HTML] Phylotranscriptomics suggests the jawed vertebrate ancestor could generate diverse helper and regulatory T cell subsets
Background The cartilaginous fishes diverged from other jawed vertebrates~ 450 million
years ago (mya). Despite this key evolutionary position, the only high-quality cartilaginous …
years ago (mya). Despite this key evolutionary position, the only high-quality cartilaginous …
Deiminated proteins and extracellular vesicles-novel serum biomarkers in whales and orca
Peptidylarginine deiminases (PADs) are a family of phylogenetically conserved calcium-
dependent enzymes which cause post-translational protein deimination. This can result in …
dependent enzymes which cause post-translational protein deimination. This can result in …
Deiminated proteins in extracellular vesicles and plasma of nurse shark (Ginglymostoma cirratum)-novel insights into shark immunity
Peptidylarginine deiminases (PADs) are phylogenetically conserved calcium-dependent
enzymes which post-translationally convert arginine into citrulline in target proteins in an …
enzymes which post-translationally convert arginine into citrulline in target proteins in an …
[HTML][HTML] Exploration of the Nurse Shark (Ginglymostoma cirratum) Plasma Immunoproteome Using High-Resolution LC-MS/MS
Many animals of scientific importance lack species-specific reagents (eg, monoclonal
antibodies) for in-depth studies of immune proteins. Mass spectrometry (MS)-based …
antibodies) for in-depth studies of immune proteins. Mass spectrometry (MS)-based …
[HTML][HTML] Plasma proteome responses in salmonid fish following immunization
Vaccination plays a critical role in the protection of humans and other animals from
infectious diseases. However, the same vaccine often confers different protection levels …
infectious diseases. However, the same vaccine often confers different protection levels …
[HTML][HTML] Plasma proteomic profiling of bacterial cold water disease-resistant and-susceptible rainbow trout lines and biomarker discovery
GD Wiens, DP Marancik, CC Chadwick… - Frontiers in …, 2023 - frontiersin.org
Genetic variation for disease resistance is present in salmonid fish; however, the molecular
basis is poorly understood, and biomarkers of disease susceptibility/resistance are …
basis is poorly understood, and biomarkers of disease susceptibility/resistance are …