[HTML][HTML] Infections and pregnancy: effects on maternal and child health

M Kumar, M Saadaoui, S Al Khodor - Frontiers in Cellular and …, 2022 - frontiersin.org
Pregnancy causes physiological and immunological adaptations that allow the mother and
fetus to communicate with precision in order to promote a healthy pregnancy. At the same …

[HTML][HTML] Poor birth outcomes in malaria in pregnancy: recent insights into mechanisms and prevention approaches

CLL Chua, W Hasang, SJ Rogerson, A Teo - Frontiers in immunology, 2021 - frontiersin.org
Pregnant women in malaria-endemic regions are susceptible to malaria in pregnancy, which
has adverse consequences on birth outcomes, including having small for gestational age …

[HTML][HTML] Approaches to address the anemia challenge

CU Loechl, A Datta-Mitra, L Fenlason, R Green… - The Journal of …, 2023 - Elsevier
Anemia is a multifactorial condition; approaches to address it must recognize that the causal
factors represent an ecology consisting of internal (biology, genetics, and health) and …

Pathogenicity and virulence of malaria: Sticky problems and tricky solutions

IS Walker, SJ Rogerson - Virulence, 2023 - Taylor & Francis
Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths
each year, concentrated in Africa and in young children, but much of the world's population …

[HTML][HTML] Progress and insights toward an effective placental malaria vaccine

B Gamain, A Chêne, NK Viebig… - Frontiers in …, 2021 - frontiersin.org
In areas where Plasmodium falciparum transmission is endemic, clinical immunity against
malaria is progressively acquired during childhood and adults are usually protected against …

[HTML][HTML] Placental malaria

AK Zakama, N Ozarslan, SL Gaw - Current tropical medicine reports, 2020 - Springer
Abstract Purpose of Review Placental malaria is the primary mechanism through which
malaria in pregnancy causes adverse perinatal outcomes. This review summarizes recent …

[HTML][HTML] Acquisition of complement fixing antibodies targeting Plasmodium falciparum merozoites in infants and their mothers in Uganda

SE Mortazavi, A Lugaajju, M Nylander… - Frontiers in …, 2023 - frontiersin.org
Background Antibody-mediated complement fixation has previously been associated with
protection against malaria in naturally acquired immunity. However, the process of early-life …

[HTML][HTML] Modelling the human placental interface in vitro—a review

M Cherubini, S Erickson, K Haase - Micromachines, 2021 - mdpi.com
Acting as the primary link between mother and fetus, the placenta is involved in regulating
nutrient, oxygen, and waste exchange; thus, healthy placental development is crucial for a …

Multi-functional antibody profiling for malaria vaccine development and evaluation

DH Opi, L Kurtovic, JA Chan, JL Horton… - Expert Review of …, 2021 - Taylor & Francis
Introduction A vaccine would greatly accelerate current global efforts toward malaria
elimination. While a partially efficacious vaccine has been achieved for Plasmodium …

Anopheles salivary antigens as serological biomarkers of vector exposure and malaria transmission: A systematic review with multilevel modelling

EA Kearney, PA Agius, V Chaumeau, JC Cutts… - Elife, 2021 - elifesciences.org
Background: Entomological surveillance for malaria is inherently resource-intensive and
produces crude population-level measures of vector exposure which are insensitive in low …