Bisphenol A: an endocrine disruptor with widespread exposure and multiple effects

BS Rubin - The Journal of steroid biochemistry and molecular …, 2011 - Elsevier
Bisphenol A (BPA) is one of the highest volume chemicals produced worldwide. This
compound is a building block of polycarbonate plastics often used for food and beverage …

Endocrine-disrupting chemicals: an Endocrine Society scientific statement

E Diamanti-Kandarakis, JP Bourguignon… - Endocrine …, 2009 - academic.oup.com
There is growing interest in the possible health threat posed by endocrine-disrupting
chemicals (EDCs), which are substances in our environment, food, and consumer products …

Endocrine‐disrupting chemicals: associated disorders and mechanisms of action

S De Coster, N Van Larebeke - Journal of environmental and …, 2012 - Wiley Online Library
The incidence and/or prevalence of health problems associated with endocrine‐disruption
have increased. Many chemicals have endocrine‐disrupting properties, including bisphenol …

Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses

LN Vandenberg, T Colborn, TB Hayes… - Endocrine …, 2012 - academic.oup.com
For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional
concepts in toxicology, in particular the dogma of “the dose makes the poison,” because …

Environmental causes of cancer: endocrine disruptors as carcinogens

AM Soto, C Sonnenschein - Nature Reviews Endocrinology, 2010 - nature.com
Environmental endocrine disrupting chemicals (EDCs), including pesticides and industrial
chemicals, have been and are released into the environment producing deleterious effects …

Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development

DC Dolinoy, D Huang, RL Jirtle - Proceedings of the …, 2007 - National Acad Sciences
The hypothesis of fetal origins of adult disease posits that early developmental exposures
involve epigenetic modifications, such as DNA methylation, that influence adult disease …

In vivo effects of bisphenol A in laboratory rodent studies

CA Richter, LS Birnbaum, F Farabollini… - Reproductive …, 2007 - Elsevier
Concern is mounting regarding the human health and environmental effects of bisphenol A
(BPA), a high-production-volume chemical used in synthesis of plastics. We have reviewed …

[HTML][HTML] Bisphenol A and hormone-associated cancers: current progress and perspectives

H Gao, BJ Yang, N Li, LM Feng, XY Shi, WH Zhao… - Medicine, 2015 - journals.lww.com
Bisphenol A (BPA), a carbon-based synthetic compound, exhibits hormone-like properties
and is present ubiquitously in the environment and in human tissues due to its widespread …

Environmental factors, epigenetics, and developmental origin of reproductive disorders

SM Ho, A Cheong, MA Adgent, J Veevers… - Reproductive …, 2017 - Elsevier
Sex-specific differentiation, development, and function of the reproductive system are largely
dependent on steroid hormones. For this reason, developmental exposure to estrogenic and …

Perinatal exposure to bisphenol a alters early adipogenesis in the rat

E Somm, VM Schwitzgebel, A Toulotte… - Environmental …, 2009 - ehp.niehs.nih.gov
Background The causes of the current obesity pandemic have not been fully elucidated.
Implication of environmental endocrine disruptors such as bisphenol A (BPA) on adipose …