Biobank-driven genomic discovery yields new insight into atrial fibrillation biology

JB Nielsen, RB Thorolfsdottir, LG Fritsche, W Zhou… - Nature …, 2018 - nature.com
To identify genetic variation underlying atrial fibrillation, the most common cardiac
arrhythmia, we performed a genome-wide association study of> 1,000,000 people, including …

Genome-wide analysis yields new loci associating with aortic valve stenosis

A Helgadottir, G Thorleifsson, S Gretarsdottir… - Nature …, 2018 - nature.com
Aortic valve stenosis (AS) is the most common valvular heart disease, and valve
replacement is the only definitive treatment. Here we report a large genome-wide …

Genome-wide association study of 1 million people identifies 111 loci for atrial fibrillation

JB Nielsen, RB Thorolfsdottir, LG Fritsche, W Zhou… - bioRxiv, 2018 - biorxiv.org
To understand the genetic variation underlying atrial fibrillation (AF), the most common
cardiac arrhythmia, we performed a genome-wide association study (GWAS) of> 1 million …