[HTML][HTML] Setting a stage: Inflammation during preeclampsia and postpartum

O Herrock, E Deer, B LaMarca - Frontiers in Physiology, 2023 - frontiersin.org
Preeclampsia (PE) is a leading cause of maternal and fetal mortality worldwide. The immune
system plays a critical role in normal pregnancy progression; however, inappropriate …

The Role of ncRNAs in the Immune Dysregulation of Preeclampsia

C Mora-Palazuelos, CE Villegas-Mercado… - International Journal of …, 2023 - mdpi.com
The main complications causing practically 75% of all maternal deaths are severe bleeding,
infections, and high blood pressure during pregnancy (preeclampsia (PE) and eclampsia) …

New immune horizons in therapeutics and diagnostic approaches to Preeclampsia

I Mukherjee, S Singh, A Karmakar… - American Journal of …, 2023 - Wiley Online Library
Hypertensive disorders of pregnancy (HDP) are one of the commonest maladies, affecting
5%–10% of pregnancies worldwide. The American College of Obstetricians and …

Anti-angiogenic mechanisms and serotonergic dysfunction in the Rgs2 knockout model for the study of psycho-obstetric risk

SB Gumusoglu, MD Kiel, A Gugel… - …, 2024 - nature.com
Psychiatric and obstetric diseases are growing threats to public health and share high rates
of co-morbidity. G protein-coupled receptor signaling (eg, vasopressin, serotonin) may be a …

Increased fetal microchimerism in immune and stem cell subsets in preeclampsia

SA McCartney, T Kolarova, SB Kanaan… - American Journal of …, 2023 - Wiley Online Library
Problem Preeclampsia (PE) is associated with an increased risk of maternal cardiovascular
disease (CVD), however, it is unclear whether this is due to shared underlying physiology or …

Low indoleamine 2, 3 dioxygenase (IDO) activity is associated with psycho-obstetric risk

S Gumusoglu, CR Meincke, M Kiel, A Betz… - Pregnancy …, 2024 - Elsevier
Objectives Preeclampsia and depression in pregnancy are among the most prevalent
obstetric disorders with no known cures. While depression and preeclampsia each increase …

Update on immune mechanisms in hypertension

S Navaneethabalakrishnan, HL Smith… - American Journal of …, 2022 - academic.oup.com
The contribution of immune cells in the initiation and maintenance of hypertension is
undeniable. Several studies have established the association between hypertension …

Identification of (−)-Epigallocateshin gallate derivatives promoting innate immune activation via 2′, 3′-cyclic GMP-AMP-stimulator of interferon genes pathway

H Lee, JH Jeong, T Lee, Y Chong, H Choo… - Bioorganic & Medicinal …, 2023 - Elsevier
Epigallocatehin-3-gallate (EGCG) is a catechin derived from green tea, which has been
widely studied for its anti-oxidant and anti-tumor properties. Although EGCG plays important …

Maternal and fetal mitochondrial gene dysregulation in hypertensive disorders of pregnancy

CA Ricci, DM Reid, J Sun, DA Santillan… - Physiological …, 2023 - journals.physiology.org
Mitochondrial dysfunction has been implicated in pregnancy-induced hypertension (PIH).
The role of mitochondrial gene dysregulation in PIH, and consequences for maternal-fetal …

[HTML][HTML] An Update Review of the Pathogenesis Hypothesis in Preeclampsia

R Lian, BS Zhu, X Zeng - Clinical and Experimental Obstetrics & …, 2022 - imrpress.com
Objectives: Hypertensive disorders occur in approximately 12% to 22% of pregnancies and
cause substantial perinatal morbidity and mortality of both mother and fetus. Hypertensive …