CRISPR crops: plant genome editing toward disease resistance

T Langner, S Kamoun, K Belhaj - Annual review of …, 2018 - annualreviews.org
Genome editing by sequence-specific nucleases (SSNs) has revolutionized biology by
enabling targeted modifications of genomes. Although routine plant genome editing …

Pivoting the plant immune system from dissection to deployment

JL Dangl, DM Horvath, BJ Staskawicz - Science, 2013 - science.org
Diverse and rapidly evolving pathogens cause plant diseases and epidemics that threaten
crop yield and food security around the world. Research over the last 25 years has led to an …

Genome-edited powdery mildew resistance in wheat without growth penalties

S Li, D Lin, Y Zhang, M Deng, Y Chen, B Lv, B Li, Y Lei… - Nature, 2022 - nature.com
Disruption of susceptibility (S) genes in crops is an attractive breeding strategy for conferring
disease resistance,. However, S genes are implicated in many essential biological functions …

Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew

Y Wang, X Cheng, Q Shan, Y Zhang, J Liu, C Gao… - Nature …, 2014 - nature.com
Sequence-specific nucleases have been applied to engineer targeted modifications in
polyploid genomes, but simultaneous modification of multiple homoeoalleles has not been …

The enhancement of plant disease resistance using CRISPR/Cas9 technology

VMG Borrelli, V Brambilla, P Rogowsky… - Frontiers in plant …, 2018 - frontiersin.org
Genome editing technologies have progressed rapidly and become one of the most
important genetic tools in the implementation of pathogen resistance in plants. Recent years …

The PTI to ETI Continuum in Phytophthora-Plant Interactions

ZA Naveed, X Wei, J Chen, H Mubeen… - Frontiers in plant …, 2020 - frontiersin.org
Phytophthora species are notorious pathogens of several economically important crop
plants. Several general elicitors, commonly referred to as Pathogen-Associated Molecular …

Susceptibility genes 101: how to be a good host

CCN van Schie, FLW Takken - Annual review of phytopathology, 2014 - annualreviews.org
To confer resistance against pathogens and pests in plants, typically dominant resistance
genes are deployed. However, because resistance is based on recognition of a single …

CRISPR/Cas9-targeted mutagenesis of the tomato susceptibility gene PMR4 for resistance against powdery mildew

MI Santillán Martínez, V Bracuto, E Koseoglou… - BMC plant biology, 2020 - Springer
Background The development of CRISPR/Cas9 technology has facilitated targeted
mutagenesis in an efficient and precise way. Previously, RNAi silencing of the susceptibility …

mlo-Based Resistance: An Apparently Universal “Weapon” to Defeat Powdery Mildew Disease

S Kusch, R Panstruga - Molecular Plant-Microbe Interactions, 2017 - Am Phytopath Society
Loss-of-function mutations of one or more of the appropriate Mildew resistance locus o (Mlo)
genes are an apparently reliable “weapon” to protect plants from infection by powdery …

Plant behaviour under combined stress: tomato responses to combined salinity and pathogen stress

Y Bai, C Kissoudis, Z Yan, RGF Visser… - The plant …, 2018 - Wiley Online Library
Crop plants are subjected to a variety of stresses during their lifecycle, including abiotic
stress factors such as salinity and biotic stress factors such as pathogens. Plants have …