Parkinson's disease (PD) is a neurodegenerative disease characterized by a progressive
loss of dopaminergic neurons from the nigrostriatal pathway, formation of Lewy bodies, and …

Statins are widely accepted as first-choice agents for the prevention of lipid-related
cardiovascular diseases. These drugs have both anti-inflammatory and anti-oxidant …

Statins are more widely used not only for the primary and secondary prevention of
cardiovascular disease by blocking cholesterol biosynthesis but also for the potential …

Importance Drug repurposing is potentially cost-effective, low risk, and necessary in
psychiatric drug development. The availability of large, routine data sets provides the …

There are some conflicting results regarding the benefit of adjunctive therapy with statins for
severity of negative symptoms in schizophrenia. This study aimed to verify whether statins …

Elevated levels of cholesterol and its metabolites (oxysterols) have been reported to be
associated not only with several metabolic syndromes, but also become a prognostic risk …

Statins are widely being used for the treatment of a variety of conditions beyond their original
indication for lowering cholesterol. We have previously reported that simvastatin affected the …

Statins are common drugs that are clinically used to reduce elevated plasma cholesterol
levels. Based on their solubility, statins are considered to be either hydrophilic or lipophilic …

Abstract Statins, or 3-hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors, such as
lovastatin, atorvastatin, simvastatin, pravastatin, fluvastatin, rosuvastatin and pitavastatin, are …

Objective We studied the association between the statin dosage and the risk of Parkinson
disease (PD) in diabetic patients in Taiwan. Methods One million patients were randomly …