Intermittent ethanol access schedule in rats as a preclinical model of alcohol abuse
S Carnicella, D Ron, S Barak - Alcohol, 2014 - Elsevier
One of the major challenges in preclinical studies of alcohol abuse and dependence
remains the development of paradigms that will elicit high ethanol intake and mimic the …
remains the development of paradigms that will elicit high ethanol intake and mimic the …
Targeting glutamate uptake to treat alcohol use disorders
Alcoholism is a serious public health concern that is characterized by the development of
tolerance to alcohol's effects, increased consumption, loss of control over drinking and the …
tolerance to alcohol's effects, increased consumption, loss of control over drinking and the …
Dihydromyricetin as a novel anti-alcohol intoxication medication
Y Shen, AK Lindemeyer, C Gonzalez… - Journal of …, 2012 - Soc Neuroscience
Alcohol use disorders (AUDs) constitute the most common form of substance abuse. The
development of AUDs involves repeated alcohol use leading to tolerance, alcohol …
development of AUDs involves repeated alcohol use leading to tolerance, alcohol …
Primary food reward and reward‐predictive stimuli evoke different patterns of phasic dopamine signaling throughout the striatum
Phasic changes in dopamine activity play a critical role in learning and goal‐directed
behavior. Unpredicted reward and reward‐predictive cues evoke phasic increases in the …
behavior. Unpredicted reward and reward‐predictive cues evoke phasic increases in the …
Adolescent rearing conditions influence the relationship between initial anxiety‐like behavior and ethanol drinking in male Long Evans rats
AM Chappell, E Carter, BA McCool… - Alcoholism: Clinical …, 2013 - Wiley Online Library
Background Rodent studies have demonstrated that adolescent social isolation results in
many behavioral perturbations, including increases in anxiety‐like behaviors. Socially …
many behavioral perturbations, including increases in anxiety‐like behaviors. Socially …
Dexmedetomidine attenuates neurotoxicity induced by prenatal propofol exposure
Background: Anesthetic agents (eg, isoflurane, propofol) may cause neurodegeneration in
the developing brains and impair animals' learning ability. Dexmedetomidine (DEX), a …
the developing brains and impair animals' learning ability. Dexmedetomidine (DEX), a …
Dynamic c‐Fos changes in mouse brain during acute and protracted withdrawal from chronic intermittent ethanol exposure and relapse drinking
Alcohol dependence promotes neuroadaptations in numerous brain areas, leading to
escalated drinking and enhanced relapse vulnerability. We previously developed a mouse …
escalated drinking and enhanced relapse vulnerability. We previously developed a mouse …
Behavioral sensitization to ethanol: Neural basis and factors that influence its acquisition and expression
R Camarini, RM Pautassi - Brain research bulletin, 2016 - Elsevier
Ethanol-induced behavioral sensitization (EBS) was first described in 1980, approximately
10 years after the phenomenon was described for psychostimulants. Ethanol acts on γ …
10 years after the phenomenon was described for psychostimulants. Ethanol acts on γ …
[HTML][HTML] Chronic intermittent voluntary alcohol drinking induces hyperalgesia in Sprague-Dawley rats
The mechanisms of hyperalgesia in alcoholics are not completely clear, and the
development of animal models would therefore be necessary in investigating the underlying …
development of animal models would therefore be necessary in investigating the underlying …
Micro RNA expression profile and functional analysis reveal that mi R‐382 is a critical novel gene of alcohol addiction
Alcohol addiction is a major social and health concern. Here, we determined the expression
profile of microRNAs (miRNAs) in the nucleus accumbens (NAc) of rats treated with alcohol …
profile of microRNAs (miRNAs) in the nucleus accumbens (NAc) of rats treated with alcohol …