Genetic estimates of contemporary effective population size: what can they tell us about the importance of genetic stochasticity for wild population persistence?

FP Palstra, DE Ruzzante - Molecular ecology, 2008 - Wiley Online Library
Genetic stochasticity due to small population size contributes to population extinction,
especially when population fragmentation disrupts gene flow. Estimates of effective …

Dietary restriction in rats and mice: a meta-analysis and review of the evidence for genotype-dependent effects on lifespan

WR Swindell - Ageing research reviews, 2012 - Elsevier
Laboratory survival experiments have shown that dietary restriction (DR) can increase
median and maximum lifespan. This paper provides a meta-analysis of laboratory …

Multiplex Manager 1.0: a cross-platform computer program that plans and optimizes multiplex PCR

CE Holleley, PG Geerts - BioTechniques, 2009 - Taylor & Francis
Multiplex Manager 1.0 is a user-friendly cross-platform program that designs efficient
combinations of existing genetic marker loci into multiplex polymerase chain reactions and …

Conservation genetics of population bottlenecks: the role of chance, selection, and history

JL Bouzat - Conservation Genetics, 2010 - Springer
Conservation genetics studies of populations bottlenecks are commonly framed under the
detrimental paradigm of inbreeding depression. This conceptual paradigm presupposes a …

Role of inbreeding depression and purging in captive breeding and restoration programmes

PL Leberg, BD Firmin - Molecular Ecology, 2008 - Wiley Online Library
Inbreeding depression is a major force affecting the evolution and viability of small
populations in captive breeding and restoration programmes. Populations that experience …

Establishment and characterisation of salmon louse (Lepeophtheirus salmonis (Krøyer 1837)) laboratory strains

LA Hamre, KA Glover, F Nilsen - Parasitology international, 2009 - Elsevier
The salmon louse (Lepeophtheirus salmonis (Krøyer 1837)) is an ectoparasitic copepod
which represents a major pathogen of wild and farmed salmonid fishes in the marine …

Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's …

R Gordon, N Singh, V Lawana, A Ghosh… - Neurobiology of …, 2016 - Elsevier
Chronic microglial activation has been linked to the progressive degeneration of the
nigrostriatal dopaminergic neurons evidenced in Parkinson's disease (PD) pathogenesis …

The influence of developmental diet on reproduction and metabolism in Drosophila

P Klepsatel, D Knoblochová, TN Girish… - BMC evolutionary …, 2020 - Springer
Background The adaptive significance of phenotypic changes elicited by environmental
conditions experienced early in life has long attracted attention in evolutionary biology. In …

Mating system shifts on the trailing edge

DA Levin - Annals of Botany, 2012 - academic.oup.com
Background The trailing edges of species ranges are becoming a subject of increasing
interest as the environment changes due to global warming. Trailing edge populations are …

Long-term exhaustion of the inbreeding load in Drosophila melanogaster

N Pérez-Pereira, R Pouso, A Rus, A Vilas… - Heredity, 2021 - nature.com
Inbreeding depression, the decline in fitness of inbred individuals, is a ubiquitous
phenomenon of great relevance in evolutionary biology and in the fields of animal and plant …