Modulation of host immunity by helminths: the expanding repertoire of parasite effector molecules
Helminths are extraordinarily successful parasites due to their ability to modulate the host
immune response. They have evolved a spectrum of immunomodulatory molecules that are …
immune response. They have evolved a spectrum of immunomodulatory molecules that are …
Looking beyond the induction of Th2 responses to explain immunomodulation by helminths
TB Nutman - Parasite immunology, 2015 - Wiley Online Library
Although helminth infections are characteristically associated with Th2‐mediated responses
that include the production of the prototypical cytokines IL‐4, IL‐5 and IL‐13 by CD 4+ cells …
that include the production of the prototypical cytokines IL‐4, IL‐5 and IL‐13 by CD 4+ cells …
Serum amyloid A is a soluble pattern recognition receptor that drives type 2 immunity
The molecular basis for the propensity of a small number of environmental proteins to
provoke allergic responses is largely unknown. Herein, we report that mite group 13 …
provoke allergic responses is largely unknown. Herein, we report that mite group 13 …
Echinococcus–host interactions at cellular and molecular levels
K Brehm, U Koziol - Advances in parasitology, 2017 - Elsevier
The potentially lethal zoonotic diseases alveolar and cystic echinococcosis are caused by
the metacestode larval stages of the tapeworms Echinococcus multilocularis and …
the metacestode larval stages of the tapeworms Echinococcus multilocularis and …
Secreted venom allergen-like proteins of helminths: Conserved modulators of host responses in animals and plants
RHP Wilbers, R Schneiter, MHM Holterman… - PLoS …, 2018 - journals.plos.org
Despite causing considerable damage to host tissue at the onset of parasitism, invasive
helminths establish remarkably persistent infections in both animals and plants. Secretions …
helminths establish remarkably persistent infections in both animals and plants. Secretions …
Evaluation of the immunoprotective effects of eight recombinant proteins from Baylisascaris schroederi in mice model
L Xiong, L Chen, Y Chen, N Shen, R Hua, G Yang - Parasites & Vectors, 2023 - Springer
Background Baylisascaris schroederi is the most common and harmful intestinal parasitic
nematode of giant pandas, causing ascariasis. Although drug deworming is the main …
nematode of giant pandas, causing ascariasis. Although drug deworming is the main …
Fluorescent labeling of helminth extracellular vesicles using an in vivo whole organism approach
AT Boysen, B Whitehead, A Stensballe, A Carnerup… - Biomedicines, 2020 - mdpi.com
In the last two decades, extracellular vesicles (EVs) from the three domains of life, Archaea,
Bacteria and Eukaryotes, have gained increasing scientific attention. As such, the role of …
Bacteria and Eukaryotes, have gained increasing scientific attention. As such, the role of …
The FAR protein family of parasitic nematodes
SC Parks, S Nguyen, MJ Boulanger… - PLoS …, 2022 - journals.plos.org
Fatty acid–and retinol-binding proteins (FARs) belong to a unique family of
excreted/secreted proteins (ESPs) found exclusively in nematodes. Much of our …
excreted/secreted proteins (ESPs) found exclusively in nematodes. Much of our …
Evolutionary analysis of species-specific duplications in flatworm genomes
M Langleib, J Calvelo, A Costábile, E Castillo… - Molecular Phylogenetics …, 2024 - Elsevier
Platyhelminthes, also known as flatworms, is a phylum of bilaterian invertebrates infamous
for their parasitic representatives. The classes Cestoda, Monogenea, and Trematoda …
for their parasitic representatives. The classes Cestoda, Monogenea, and Trematoda …
Body fluid from the parasitic worm Ascaris suum inhibits broad‐acting pro‐inflammatory programs in dendritic cells
P Arora, JM Moll, D Andersen, CT Workman… - …, 2020 - Wiley Online Library
Dendritic cells (DCs) are essential for generating T‐cell‐based immune responses through
sensing of potential inflammatory and metabolic cues in the local environment. However …
sensing of potential inflammatory and metabolic cues in the local environment. However …