Quantitative phase imaging: recent advances and expanding potential in biomedicine

TL Nguyen, S Pradeep, RL Judson-Torres, J Reed… - ACS …, 2022 - ACS Publications
Quantitative phase imaging (QPI) is a label-free, wide-field microscopy approach with
significant opportunities for biomedical applications. QPI uses the natural phase shift of light …

Quantitative phase imaging in biomedicine

YK Park, C Depeursinge, G Popescu - Nature photonics, 2018 - nature.com
Quantitative phase imaging (QPI) has emerged as a valuable method for investigating cells
and tissues. QPI operates on unlabelled specimens and, as such, is complementary to …

Spatial light interference microscopy (SLIM)

Z Wang, L Millet, M Mir, H Ding, S Unarunotai… - Optics express, 2011 - opg.optica.org
We present spatial light interference microscopy (SLIM) as a new optical microscopy
technique, capable of measuring nanoscale structures and dynamics in live cells via …

[HTML][HTML] Invited review article: pump-probe microscopy

MC Fischer, JW Wilson, FE Robles… - Review of Scientific …, 2016 - pubs.aip.org
Multiphoton microscopy has rapidly gained popularity in biomedical imaging and materials
science because of its ability to provide three-dimensional images at high spatial and …

Diffraction phase microscopy for quantifying cell structure and dynamics

G Popescu, T Ikeda, RR Dasari, MS Feld - Optics letters, 2006 - opg.optica.org
We have developed diffraction phase microscopy as a new technique for quantitative phase
imaging of biological structures. The method combines the principles of common path …

Quantitative micro-elastography: imaging of tissue elasticity using compression optical coherence elastography

KM Kennedy, L Chin, RA McLaughlin, B Latham… - Scientific reports, 2015 - nature.com
Probing the mechanical properties of tissue on the microscale could aid in the identification
of diseased tissues that are inadequately detected using palpation or current clinical …

In-line holographic microscopy with model-based analysis

C Martin, LE Altman, S Rawat, A Wang… - Nature Reviews …, 2022 - nature.com
An in-line holographic microscope is an optical microscope outfitted with a coherent light
source, such as a laser. Light scattered by the specimen interferes with the transmitted …

Optical imaging of cell mass and growth dynamics

G Popescu, YK Park, N Lue… - … of Physiology-Cell …, 2008 - journals.physiology.org
Using novel interferometric quantitative phase microscopy methods, we demonstrate that the
surface integral of the optical phase associated with live cells is invariant to cell water …

Method and apparatus for performing optical imaging using frequency-domain interferometry

SH Yun, BE Bouma, GJ Tearney, JF De Boer - US Patent 7,733,497, 2010 - Google Patents
3,090,753 3,601.480 3,856,000 3,872.407 3,941,121 3,973,219 3,983,507 4,030,827
4,140,364 4,141,362 4,224,929 4,295,738 4,300,816 4,303.300 4,428,643 4,479,499 …

System and method for optical coherence imaging

M Shishkov, BE Bouma, GJ Tearney - US Patent 7,366,376, 2008 - Google Patents
Apparatus and method are provided for transmitting at least one electro-magnetic radiation
is provided. In particular, at least one optical fiber having at least one end extending along a …