Highlights•Incidence of lung disease caused by non-TB mycobacteria (NTM) is
increasing.•Current treatments are ineffective.•There is an urgent need to establish a drug …

Galleria mellonella (greater wax moth) larvae are used widely as surrogate infectious
disease models, due to ease of use and the presence of an innate immune system …

The increased resistance of bacteria against conventional pharmaceutical solutions, the
antibiotics, has raised serious health concerns. This has stimulated interest in the …

Cancer chemotherapy is frequently hampered by drug resistance, so the resistance to
anticancer agents represents one of the major obstacles for the effective cancer treatment …

Mycobacterium tuberculosis kills more people than any other bacterial pathogen and is
becoming increasingly untreatable due to the emergence of resistance. Verapamil, an FDA …

Herein, we report a greener protocol for the synthesis of 3‐Se/S‐indoles and imidazo [1, 2‐
a] pyridines through direct C (sp2)− H bond chalcogenation of heteroarenes with half molar …

Among the various bacterial infections, tuberculosis continues to hold center stage. Its
causative agent, Mycobacterium tuberculosis, possesses robust defense mechanisms …

Azepane-based compounds showed a variety of pharmacological properties, and its
derivatives possess a high degree of structural diversity, and it is useful for the discovery of …

Bacterial infections are characterized by their rapid and widespread proliferation, leading to
significant morbidity. Despite the availability of a variety of antimicrobial drugs, the …

The search for efficient antimicrobial therapies that can alleviate suffering caused by
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …