Brain endocannabinoid (eCB) signalling influences the motivation for natural rewards (such
as palatable food, sexual activity and social interaction) and modulates the rewarding effects …

The endocannabinoid signaling system is a widespread, neuromodulatory system in brain
and is also widely utilized in the periphery to modulate metabolic functions and the immune …

Rewards are both “liked” and “wanted,” and those 2 words seem almost interchangeable.
However, the brain circuitry that mediates the psychological process of “wanting” a particular …

Although numerous studies provide general support for the importance of genetic factors in
the risk for alcohol use disorders (AUDs), candidate gene and genome-wide studies have …

The endogenous cannabinoid system is an important regulatory system involved in
physiological homeostasis. Endocannabinoid signaling is known to modulate neural …

Since 2005, a rapidly expanding literature has evaluated whether environmental factors
such as socio-cultural context and adversity interact with genetic influences on drinking …

Background The main neurobiological theories of the development of addiction, including
tolerance, sensitization, incentive-sensitization, and allostasis, have not been tested in …

Abnormal and Clinical Psychology aims to introduce and evaluate the conceptual models of
mental health problems and their treatment, as well as to provide valuable analyses of …

Over the past fifty years a significant body of evidence has been compiled suggesting an
interaction between the endocannabinoid (EC) system and alcohol dependence. However …

Brain cannabinoid CB 1 receptors contribute to alcohol-related behaviors in experimental
animals, but their potential role in humans with alcohol dependence is poorly understood …