A role for metabolomics in the antidoping toolbox?

L Narduzzi, G Dervilly, M Audran… - Drug testing and …, 2020 - Wiley Online Library
Evidence of the continuous rise of novel doping agents and novel doping strategies calls for
the development of more accurate multi‐target screening methods. Direct multi‐target …

Doping control analysis at the Rio 2016 Olympic and Paralympic Games

HMG Pereira, VF Sardela, MC Padilha… - Drug testing and …, 2017 - Wiley Online Library
This paper summarises the results obtained from the doping control analyses performed
during the Summer XXXI Olympic Games (August 3–21, 2016) and the XV Paralympic …

Development of extractive electrospray ionization ion trap mass spectrometry for in vivo breath analysis

J Ding, S Yang, D Liang, H Chen, Z Wu, L Zhang… - Analyst, 2009 - pubs.rsc.org
In metabolomics studies and clinical diagnosis, interest is increasing in the rapid analysis of
exhaled breath. In vivo breath analysis offers a unique, unobtrusive, non-invasive method of …

Detection of designer steroid methylstenbolone in “nutritional supplement” using gas chromatography and tandem mass spectrometry: elucidation of its urinary …

G de Albuquerque Cavalcanti, FD Leal, BC Garrido… - Steroids, 2013 - Elsevier
The use of “nutritional supplements” containing unapproved substances has become a
regular practice in amateur and professional athletes. This represents a dangerous habit for …

Analytical challenges in doping control: Comprehensive two-dimensional gas chromatography with time of flight mass spectrometry, a promising option

AI Silva Jr, HMG Pereira, A Casilli… - … of Chromatography A, 2009 - Elsevier
Doping control screening based on the enhanced resolution of comprehensive two-
dimensional (2D) gas chromatography hyphenated to time of flight mass spectrometer was …

Thermodynamic-based retention time predictions of endogenous steroids in comprehensive two-dimensional gas chromatography

ACA Silva, H Ebrahimi-Najafadabi… - Analytical and …, 2015 - Springer
This work evaluates the application of a thermodynamic model to comprehensive two-
dimensional gas chromatography (GC× GC) coupled with time-of-flight mass spectrometry …

Stimulant doping agents used in Brazil: prevalence, detectability, analytical implications, and challenges

HMG Pereira, VF Sardela - Substance use & misuse, 2014 - Taylor & Francis
This article presents the prevalence of stimulant doping among Brazilian athletes, the
analytical approaches used, as well as a general evolution of the detectability of the …

Analysis of sibutramine metabolites as N-trifluoroacetamide and O-trimethylsilyl derivatives by gas chromatography–mass spectrometry in urine

VF Sardela, MTR Motta, MC Padilha… - … of Chromatography B, 2009 - Elsevier
A method for identifying the metabolites of sibutramine 1-(4 (chlorophenyl)-N, N-dimethyl-α-
(2-methylpropyl)) cyclobutanemethanamine) in urine, utilizing a double derivatization …

Detection of new exemestane metabolites by liquid chromatography interfaced to electrospray-tandem mass spectrometry

G de Albuquerque Cavalcanti, BC Garrido… - The Journal of steroid …, 2011 - Elsevier
Exemestane is an irreversible aromatase inhibitor used for anticancer therapy.
Unfortunately, this drug is also misused in sports to avoid some adverse effects caused by …

Consequences of the formation of 3, 4-dimethyl-5-phenyl-1, 3-oxazolidine on the analysis of ephedrines in urine by gas chromatography and a new method for …

VF Sardela, PDO Sardela, HMG Pereira… - … of Chromatography A, 2011 - Elsevier
The compound 3, 4-dimethyl-5-phenyl-1, 3-oxazolidine can appear as an artifact during the
gas chromatographic analysis of ephedrines. Its presence is a risk for doping control and …