Immunogenic cell death activates the tumor immune microenvironment to boost the immunotherapy efficiency

Z Li, X Lai, S Fu, L Ren, H Cai, H Zhang, Z Gu… - Advanced …, 2022 - Wiley Online Library
Tumor immunotherapy is only effective in a fraction of patients due to a low response rate
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …

Metal–organic frameworks for biological applications

I Abánades Lázaro, X Chen, M Ding… - Nature Reviews …, 2024 - nature.com
Metal–organic frameworks (MOFs) have emerged as exciting potential new candidates for
application across nanomedicine, with the first example now in a phase II human clinical …

Nanoscale MOFs: From synthesis to drug delivery and theranostics applications

M Ding, W Liu, R Gref - Advanced Drug Delivery Reviews, 2022 - Elsevier
Since the first report in 1989, Metal-Organic Frameworks (MOFs) self-assembled from metal
ions or clusters, as well as organic linkers, have attracted extensive attention. Due to their …

Targeted drug delivery strategies for precision medicines

MT Manzari, Y Shamay, H Kiguchi, N Rosen… - Nature Reviews …, 2021 - nature.com
Progress in the field of precision medicine has changed the landscape of cancer therapy.
Precision medicine is propelled by technologies that enable molecular profiling, genomic …

Mito‐bomb: targeting mitochondria for cancer therapy

X Guo, N Yang, W Ji, H Zhang, X Dong… - Advanced …, 2021 - Wiley Online Library
Cancer has been one of the most common life‐threatening diseases for a long time.
Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) …

High-resolution X-ray luminescence extension imaging

X Ou, X Qin, B Huang, J Zan, Q Wu, Z Hong, L Xie… - Nature, 2021 - nature.com
Current X-ray imaging technologies involving flat-panel detectors have difficulty in imaging
three-dimensional objects because fabrication of large-area, flexible, silicon-based …

[HTML][HTML] The application of nanoparticles in cancer immunotherapy: Targeting tumor microenvironment

M Yang, J Li, P Gu, X Fan - Bioactive materials, 2021 - Elsevier
The tumor development and metastasis are closely related to the structure and function of
the tumor microenvironment (TME). Recently, TME modulation strategies have attracted …

Supramolecular cancer nanotheranostics

J Zhou, L Rao, G Yu, TR Cook, X Chen… - Chemical Society …, 2021 - pubs.rsc.org
Among the many challenges in medicine, the treatment and cure of cancer remains an
outstanding goal given the complexity and diversity of the disease. Nanotheranostics, the …

Recent progress of chemodynamic therapy-induced combination cancer therapy

X Wang, X Zhong, Z Liu, L Cheng - Nano Today, 2020 - Elsevier
Chemodynamic therapy (CDT) is an emerging cancer treatment strategy that uses CDT
agents to convert hydrogen peroxide (H 2 O 2) into the hydroxyl radical (radical dotOH), the …

One-step integration of tumor microenvironment-responsive calcium and copper peroxides nanocomposite for enhanced chemodynamic/ion-interference therapy

B Liu, Y Bian, S Liang, M Yuan, S Dong, F He, S Gai… - ACS …, 2021 - ACS Publications
Recently, various metal peroxide nanomaterials have drawn increasing attention as an
efficient hydrogen peroxide (H2O2) self-supplying agent for enhanced tumor therapy …