While hydrogen plays an ever-increasing role in modern society, nature has utilized
hydrogen since a very long time as an energy carrier and storage molecule. Among the …

Hydrogenase enzymes efficiently process H2 and protons at organometallic FeFe, NiFe, or
Fe active sites. Synthetic modeling of the many H2ase states has provided insight into …

The reaction takes place at a specialized metal center that dramatically increases the acidity
of H2 and leads to a heterolytic splitting of the molecule which is strongly accelerated by the …

Over the last 15 years, a plethora of research has provided major insights into the structure
and function of hydrogenase enzymes. This has led to the important development of …

This article sets out to review the chemistry relating to the synthesis of structural and
functional analogues of the three classes of hydrogenases. This chemistry has grown …

Proton transfer reactions involving transition metal hydride complexes are prevalent in a
number of catalytic fuel-forming reactions, where the proton transfer kinetics to or from the …

Formation of stable iron hydrides on more nucleophilic (electron-rich) metal centers than
those found in hydrogenases with CO ligands would inhibit or at least slow down function …

Hydrogen production through water splitting is one of the most promising solutions for the
storage of renewable energy.[NiFe] hydrogenases are organometallic enzymes containing …

With the price-competitiveness of solar and wind power, hydrogen technologies may be
game changers for a cleaner, defossilized, and sustainable energy future. H2 can indeed be …

This tutorial review is aimed at chemical scientists interested in understanding and
exploiting the remarkable catalytic behavior of the hydrogenases. The key structural features …